1. GPCR/G Protein
  2. Adenosine Receptor
  3. UP202-56

UP202-56 是一种腺苷类似物,是一种腺苷能激动剂。

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UP202-56 Chemical Structure

UP202-56 Chemical Structure

CAS No. : 163838-04-8

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

UP202-56 is an adenosine analogue, which is an adenosinergic agonist.

IC50 & Target

Adenosine Receptor[1][2]

体外研究
(In Vitro)

The effects of oral administration of UP202-56, an adenosine analogue, are assessed on carrageenan-induced spinal c-Fos protein expression and peripheral oedema. Oral UP202-56 (10, 30 or 50 mg/kg) dose-dependently reduces the number of carrageenan-induced c-Fos like immunoreactivity (c-Fos-LI) neurons (r=0.931. P<0.0001), with the highest dose of UP202-56 producing 72±4% reduction of the total number of carrageenan-induced spinal c-Fos-LI neurons, and 12±3% and 33±6% of reduction of control carrageenan oedema at paw and ankle levels, respectively. UP202-56 dose-dependently reduces the spinal c-Fos protein expression in carrageenan model of inflammatory pain[1]. UP202-56 is an adenosinergic agonist[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

594.70

Formula

C34H38N6O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

UP202-56 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
UP202-56
目录号:
HY-U00226
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