2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. (+/-)-Adomeglivant

(+/-)-Adomeglivant  (Synonyms: (+/-)-LY2409021)

目录号: HY-19904A
产品使用指南 技术支持

(+/-)-Adomeglivant ((+/-)-LY2409021)是一种有效且选择性的胰高血糖素受体拮抗剂，具有降低血糖的活性。(+/-)-Adomeglivant在健康人和2型糖尿病患者中均能有效降低血糖水平。(+/-)-Adomeglivant对2型糖尿病患者的胰高血糖素信号阻断耐受性良好，并能显著减少斋戒和餐后血糖，同时伴随可逆的氨基转移酶升高。(+/-)-Adomeglivant的胰高血糖素信号抑制作用是2型糖尿病患者有前景的潜在抑制方法，值得在更长的临床试验中进一步评估其益处和风险。

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(+/-)-Adomeglivant Chemical Structure

(+/-)-Adomeglivant Chemical Structure

CAS No. : 872260-47-4

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规格 是否有货
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Other Forms of (+/-)-Adomeglivant:

(+/-)-Adomeglivant 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(+/-)-Adomeglivant ((+/-)-LY2409021) is a potent and selective glucagon receptor antagonist with hypoglycemic activity. (+/-)-Adomeglivant is effective in lowering blood sugar levels in both healthy people and people with type 2 diabetes. (+/-)-Adomeglivant is well tolerated by glucagon signaling blockade in patients with type 2 diabetes and significantly reduces fasting and postprandial blood glucose with a concomitant reversible elevation of aminotransferases. Glucagon signaling inhibition by (+/-)-Adomeglivant is a promising potential inhibitory approach for patients with type 2 diabetes and warrants further evaluation of its benefits and risks in longer clinical trials[1].

分子量

555.63

Formula

C32H36F3NO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(+/-)-Adomeglivant 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

(+/-)-Adomeglivant872260-47-4(+/-)-LY2409021Endogenous MetaboliteInhibitorinhibitorinhibit

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