1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GlyT
  3. ALX-1393

ALX-1393 

目录号: HY-111029
产品使用指南

ALX-1393 是一种选择性 GlyT2 抑制剂, 对大鼠急性疼痛模型中的热,机械和化学刺激具有抗伤害作用。

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ALX-1393 Chemical Structure

ALX-1393 Chemical Structure

CAS No. : 949164-09-4

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Description

ALX-1393, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model[1].

IC50 & Target

GlyT2[1]

In Vivo

ALX1393 (i.c.v.; 25, 50, and 100 μg) in normal rats suppresses the late-phase response in the formalin test but does not affect motor performance. ALX1393 inhibits mechanical and cold hyperalgesia in a dose-dependent manner[2].

Molecular Weight

395.42

Formula

C₂₃H₂₂FNO₄

CAS No.

949164-09-4

SMILES

N[C@@H](COC(C1=CC=CC(F)=C1)C2=CC=CC=C2OCC3=CC=CC=C3)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
ALX-1393
目录号:
HY-111029
需求量:

ALX-1393

Cat. No.: HY-111029