1. Anti-infection
  2. Influenza Virus
  3. Anti-Influenza agent 4

Anti-Influenza agent 4 是一种有效且具有选择性的流感病毒 (influenza virus) 抑制剂,对 A/Roma 和 A/Parma 毒株的 EC50 分别为 150 nM 和 62 nM。

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Anti-Influenza agent 4 Chemical Structure

Anti-Influenza agent 4 Chemical Structure

CAS No. : 522625-85-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively[1].

IC50 & Target

EC50: 150±0.07 nM (A/Roma), 62±0.02 nM (A/Parma)[1]

体外研究
(In Vitro)

Anti-Influenza agent 4 (compound 5) (0-500 μM; 24 and 48 h) exhibits low cytotoxicity in MDCK cells[1].
Anti-Influenza agent 4 shows highly antiviral activity against influenza strain A/Roma and A/Parma with EC50s of 150±0.07 nM and 62±0.02 nM, respectively[1].
Anti-Influenza agent 4 shows IC50s of 244 nM and 230.7 nM against influenza strain A/Roma and A/Parma in hemolysis inhibition assay[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: MDCK cells
Concentration: 0-500 μM
Incubation Time: 24 and 48 h
Result: Exhibited low cytotoxicity with a CC50 value of 450 μM.
分子量

386.42

Formula

C19H18N2O5S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Anti-Influenza agent 4 相关分类

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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anti-Influenza agent 4
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HY-148309
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