1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 139

Antibacterial agent 139 对革兰氏阳性菌具有抗菌活性。Antibacterial agent 139 具有抗 MRSA、抗 VISA 和抗 LRSE 活性。Antibacterial agent 139 去极化细菌细胞膜。

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Antibacterial agent 139 Chemical Structure

Antibacterial agent 139 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 139 has antibacterial activity against Gram-positive bacteria. Antibacterial agent 139 has anti-MRSA, anti-VISA, and anti-LRSE activities. Antibacterial agent 139 depolarizes the bacterial cell membrane[1].

体外研究
(In Vitro)

Antibacterial agent 139 (Compound 44) (18 h) 抑制形成生物膜的金黄色葡萄球菌和表皮葡萄球菌菌株的生长,MIC 值小于 12.5 μg/mL[1]
Antibacterial agent 139 (24 h) 显示出对肺和皮肤成纤维细胞系 (MCR-5 和 BJ) 的细胞毒性,IC50 分别为 12.5 和 >25 μg/mL[1]
Antibacterial agent 139 (60 分钟) 在大鼠肝微粒体中代谢稳定,清除率较低 (8.94 μL/min/mg)[1]
Antibacterial agent 139 使细菌细胞膜去极化[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: MSSA, MSSE, SP, MRSA, VISA, LRSE
Concentration: 0-12.5 μg/mL
Incubation Time: 18 h
Result: MIC values : 3.125, 3.125, 6.25, 0.78, 3.125, 3.125 μg/mL respectively.
分子量

532.00

Formula

C28H29ClF3N3O2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Antibacterial agent 139 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Antibacterial agent 139
目录号:
HY-149095
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