2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 140 chloride

Antibacterial agent 140 chloride 是一种很有前景的抗菌剂 (antibacterial agent)。Antibacterial agent 140 chloride 是首款基于钌的 AIEgen 光敏剂，可同时用于革兰氏阳性菌 (G+) 的检测和治疗。Antibacterial agent 140 chloride 由于其与脂质胆酸(LTA)的相互作用，可用于革兰氏阳性菌 (G+) 的独特选择性鉴别和高效杀灭。 Antibacterial agent 140 chloride 对 G+ 具有较强的体外和体内光照射抑菌活性。

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Antibacterial agent 140 chloride

Antibacterial agent 140 chloride Chemical Structure

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Antibacterial agent 140 chloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 140 chloride is a promising antibacterial agent. Antibacterial agent 140 chloride is also the first Ru-based AIEgen photosensitizer for simultaneous dual applications of Gram-positive bacteria (G+) detection and treatment. Antibacterial agent 140 chloride uniquely selective discriminates and efficient exterminates Gram-positive bacteria (G+) from other bacteria due to its interaction with lipoteichoic acids (LTA). Antibacterial agent 140 chloride  also possessed robust antibacterial activity for G+ under light irradiation[1].

体外研究
(In Vitro)

Antibacterial agent 140 chloride (0.1-5 μg/mL, 1 h) 在黑暗中表现出 78%-0% 的剂量依赖性，表明 Ru2 对 S. aureus 具有暗毒性[1]。
Antibacterial agent 140 chloride（0.1-5 μg/mL；1 h) 在 120s 光照射下表现出明显的剂量依赖性和时间依赖性，Ru2 在极低浓度光照射下几乎完全抑制金黄色葡萄球菌的生长[1]。
Antibacterial agent 140 chloride（0.1-5 μg/mL；1 h) 与 HeLa 细胞孵育后，80% 以上的 HeLa 细胞存活, 在 ≤32 μM 的光照下，>73% 的 HeLa 细胞存活[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 140 chloride 相关抗体:
体内研究
(In Vivo)

Antibacterial agent 140 chloride（20 μg/mL/50 μL; 1-10 days) 使得金黄色葡萄球菌感染导致的伤口大小明显减小，雌性昆明小鼠伤口在 7 天后几乎完全愈合。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female Kunming mice (5-6 weeks old) mice model with skin infected by S. aureus.[1]
Dosage: 50 μL (20 μg/mL)
Administration: 50 μL (20 μg/mL); skin application; 1-10 days
Result: 99.50% of the infected wound areas were healed after 10 days under Ru2/light treatment.
Exhibited photodynamic antibacterial therapeutic efficacy.
分子量

1162.10

Formula

C61H44Cl2N8Ru2-
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 140 chloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 140Antibacterial agent140Antibacterial agent-140BacterialInhibitorinhibitorinhibit

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产品名称：
Antibacterial agent 140 chloride
目录号：
HY-149801A
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