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  5. Macro H2A.1 抗体 (YA3186)

Macro H2A.1 抗体 (YA3186)

目录号: HY-P83441
抗体使用指南 技术支持

Macro H2A.1 Antibody (YA3186) 是无偶联基团的、靶向 Macro H2A.1 的 IgG 抗体 (克隆号：YA3186)，预测分子量为 40 kDa (实际观测：40 kDa)。Macro H2A.1 Antibody (YA3186) 可用于小鼠、 大鼠背景下的 WB、ICC/IF 实验。

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规格 价格 是否有货 数量
10 μL ￥470 1 - 2 周
50 μL ￥1220 1 - 2 周
100 μL ￥2000 1 - 2 周
250 μL   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: 蛋白质免疫印迹; IHC-P: 石蜡切片样本的免疫组织化学; IHC-F: 冰冻切片样本的免疫组织化学; ICC/IF: 细胞免疫荧光; IF-Tissue: 组织免疫荧光; mIHC: 多重荧光免疫组化; IP: 免疫沉淀; ChIP: 染色质免疫沉淀; FC: 流式细胞术; ELISA: 酶联免疫吸附试验】

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描述

Macro H2A.1 Antibody (YA3186) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3186), targeting Macro H2A.1, with a predicted molecular weight of 40 kDa (observed band size: 40 kDa). Macro H2A.1 Antibody (YA3186) can be used for WB, ICC/IF experiment in mouse, rat background.
研究背景

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The related gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
基因 ID
蛋白数据库
中文名
Macro H2A.1 抗体 (YA3186)
同用名
H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2
分子量

Predicted band size: 40 kDa; Observed band size: 40 kDa
纯度

Affinity Purified
偶联

Non-conjugated
修饰

Unmodified
研究领域

Epigenetics and Nuclear Signaling
产品类别

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
克隆性

Recombinant, Monoclonal
宿主

Rabbit
反应物种

Mouse, Rat
推荐稀释比例

WB: 1/500-1/1000;IF: 1/50-1/200
应用

WB, ICC/IF
性状

液体
组分

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
运输条件

Shipping with blue ice.
同型

IgG
敏感性

Endogenous
免疫原

A synthetic peptide of human macroH2A.1
数据库

Entrez Gene: 9555 Human ; 26914 Mouse ; 29384 Rat

SwissProt: O75367 Human ; Q9QZQ8 Mouse ; Q02874 Rat

OMIM: 610054 Human

文件资料
抗体使用指南 (1083 KB)

Macro H2A.1 Antibody (YA3186) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号：
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