MICA+MICB 抗体 (YA3560)

MICA+MICB Antibody (YA3560) is a rabbit-derived non-conjugated IgG antibody, targeting MICA. MICA+MICB Antibody (YA3560) can be used for WB, FC, IP experiment in human background.

The related gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in The related gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of The related gene results in multiple transcript variants.

Q29980 / Q29983

Predicted band size: 43 kDa； Observed band size: 60 kDa

affinity purified

Cell membrane, Cytoplasm; Cell membrane.

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal, Recombinant

Rabbit

Human

WB: 1:2,000; FC: 1:1,000; IP: 1-2μg/sample

WB, IP, FC

K-562 cell lysate, HL-60 cell lysate, Jurkat cell lysate, HeLa cell lysate, HUVEC cell lysate, HeLa.

液体

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Recombinant protein within human MICB aa 1-309.