2. 抗体
  3. 一抗
  4. 单克隆抗体 重组抗体
  5. SLC12A1 抗体 (YA3471)

SLC12A1 抗体 (YA3471)

目录号: HY-P83742
抗体使用指南 技术支持

SLC12A1 Antibody (YA3471) 是一个兔来源、无偶联标记、抗 SLC12A1 的 IgG 单克隆抗体。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μL   询价  
100 μL   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: 蛋白质免疫印迹; IHC-P: 石蜡切片样本的免疫组织化学; IHC-F: 冰冻切片样本的免疫组织化学; ICC/IF: 细胞免疫荧光; IF-Tissue: 组织免疫荧光; mIHC: 多重荧光免疫组化; IP: 免疫沉淀; ChIP: 染色质免疫沉淀; FC: 流式细胞术; ELISA: 酶联免疫吸附试验】

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

SLC12A1 Antibody (YA3471) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLC12A1.
研究背景

The related gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in The related gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.
基因 ID
蛋白数据库
中文名
SLC12A1 抗体 (YA3471)
同用名
BSC1 antibody; Bumetanide sensitive sodium 3 antibody; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 antibody; Kidney specific Na K Cl symporter antibody; Kidney-specific Na-K-Cl symporter antibody; MGC48843 antibody; Na K 2Cl cotransporter antibody; NKCC2 antibody; potassiumchloride cotransporter 2 antibody; S12A1_HUMAN antibody; Slc12a1 antibody; sodium potassium chloride cotransporter 2 antibody; solute carrier family 12 (sodium/potassium/chloride transporters) antibody; Solute carrier family 12 member 1 antibody
分子量

Predicted band size: 121 kDa; Observed band size: 150 kDa
纯度

Affinity Purified
亚细胞定位

Cell membrane
偶联

Non-conjugated
修饰

Unmodified
研究领域

Signal Transduction
产品类别

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
克隆性

Monoclonal, Recombinant
宿主

Rabbit
反应物种

Human, Mouse, Rat
推荐稀释比例

WB: 1:2000; IHC-P: 1:20000; ICC: 1:100;mIHC: 1:3000
应用

WB, IHC-P, ICC/IF
阳性对照

Mouse kidney tissue lysate, rat kidney tissue lysate, K-562 cell lysate, mouse kidney tissue, K-562.
性状

液体
组分

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
运输条件

Shipping with blue ice.
同型

IgG
免疫原

Recombinant protein within Human SLC12A1 / NKCC2 aa 593-813 / 1,099.
数据库

Entrez Gene: 6557 Human ; 20495 Mouse ;

SwissProt: Q13621 Human ; P55014 Mouse ; P55016 Rat

OMIM: 601678 Human

文件资料
抗体使用指南 (1083 KB)

SLC12A1 Antibody (YA3471) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号：
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