2. 抗体
  3. 一抗
  4. 单克隆抗体 重组抗体
  5. TAF1 抗体 (YA2956)

TAF1 抗体 (YA2956)

目录号: HY-P83211
抗体使用指南 技术支持

TAF1 Antibody (YA2956) 是一个兔来源、无偶联标记、抗 TAF1 的 IgG 单克隆抗体。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
10 μL ￥470 1 - 2 周
50 μL ￥1220 1 - 2 周
100 μL ￥2000 1 - 2 周
250 μL   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: 蛋白质免疫印迹; IHC-P: 石蜡切片样本的免疫组织化学; IHC-F: 冰冻切片样本的免疫组织化学; ICC/IF: 细胞免疫荧光; IF-Tissue: 组织免疫荧光; mIHC: 多重荧光免疫组化; IP: 免疫沉淀; ChIP: 染色质免疫沉淀; FC: 流式细胞术; ELISA: 酶联免疫吸附试验】

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

TAF1 Antibody (YA2956) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TAF1.
研究背景

Initiation of transcription by RNA polymerase II requires the activities of more than 7 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify related general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. The related gene encodes the largest subunit of TFIID. The subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. The subunit contains two independent protein kinase domains at the N- and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. Mutations in The related gene result in Dystonia 3, torsion, X-linked, a dystonia-parkinsonism disorder. Alternative splicing of The related gene results in multiple transcript variants. The related gene is part of a complex transcription unit (TAF1/DYT3), wherein some transcript variants share exons with TAF1 as well as additional downstream DYT3 exons.
基因 ID
蛋白数据库
中文名
TAF1 抗体 (YA2956)
同用名
BA2R; CCG1; CCGS; DYT3; N TAF1; NSCL2; p250; TAF1; TAF2A; TAFII250; XDP
分子量

Predicted band size: 213 kDa; Observed band size: 300 kDa
纯度

Affinity Purified
偶联

Non-conjugated
修饰

Unmodified
研究领域

Epigenetics and Nuclear Signaling
产品类别

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
克隆性

Recombinant, Monoclonal
宿主

Rabbit
反应物种

Human, Mouse, Rat
推荐稀释比例

WB: 1:500-1:1000
应用

WB
性状

液体
组分

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
运输条件

Shipping with blue ice.
同型

IgG
敏感性

Endogenous
免疫原

A synthesized peptide derived from human TAF1
数据库

Entrez Gene: 8148 Human ; 70439 Mouse ; 287571 Rat

SwissProt: P21675 Human ; Q80UV9 Mouse ;

OMIM: 314250 Human

文件资料
抗体使用指南 (1083 KB)

TAF1 Antibody (YA2956) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号：
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