Wnt-1 抗体 (YA5101)

Wnt-1 Antibody (YA5101) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Wnt-1. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse.

WNT1 是 frizzled 家族七次跨膜受体的配体（Probable），通过促进 β-catenin 依赖性转录激活参与经典 Wnt 信号通路（PubMed:23499309，PubMed:23656646，PubMed:26902720，PubMed:28528193）。在某些发育过程中，它也是核心受体 RYK 的配体，从而触发 Wnt 信号传导（By similarity）。WNT1 在胚胎大脑和中枢神经系统（CNS）的发育中发挥重要作用（By similarity），并在成骨细胞功能、骨骼发育和骨稳态中具有关键作用（PubMed:23499309，PubMed:23656646）。

P04628

Predicted band size: 41 kDa;

affinity purified.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse

WB: 1:500-1:2000; IHC: 1:200-1:1000; ICC/IF: 1:200-1:1000; FC: 1:200-1:400; ELISA: 1:10000

WB, IHC-P, ICC/IF, FC, ELISA

液体

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant fragment of Wnt-1 expressed in E. Coli.