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  3. Anticancer agent 258

Anticancer agent 258 是一种咪唑并 [1,2-B][1,2,4] 三唑衍生物。Anticancer agent 258 可以调节核受体的活性。Anticancer agent 258 在 N2A 细胞中对 NurrEC50 为 63 nM。Anticancer agent 258 在 HEK293 细胞中,对 Nur77IC50 为 0.1 pM。Anticancer agent 258 可用于癌症、代谢疾病和神经系统疾病的研究。

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Anticancer agent 258 Chemical Structure

Anticancer agent 258 Chemical Structure

CAS No. : 2891984-12-4

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  • 生物活性

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生物活性

Anticancer agent 258 is an imidazo [1,2-B][1,2,4] triazol derivative. Anticancer agent 258 regulates the activity of nuclear receptors. Anticancer agent 258 has an EC50 of 63 nM against Nurr in N2A cells. Anticancer agent 258 has IC50 of 0.1 pM for Nur77 in HEK293 cells. Anticancer agent 258 can be used in the study of cancer, metabolic diseases and neurological disorders[1].

分子量

310.30

Formula

C17H12F2N4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anticancer agent 258
目录号:
HY-169907
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