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  3. Drug Derivative
  4. Anticancer agent 274

Anticancer agent 274 (Compound 1) 是一种 Sorafenib (HY-10201) 类似物。Anticancer agent 274 可抑制肿瘤细胞生长，对 SaOS-2 和 MNNG-HOS 细胞的 IC50 分别为 0.034 μM 和 0.042 μM。Anticancer agent 274 对正常细胞毒性较低，可用于骨肉瘤等肿瘤的研究。

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Anticancer agent 274 Chemical Structure

Anticancer agent 274 Chemical Structure

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Anticancer agent 274 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 274 (Compound 1) is a Sorafenib (HY-10201) analog. Anticancer agent 274 can inhibit the growth of tumor cells, with IC50 values of 0.034 μM and 0.042 μM against SaOS-2 and MNNG-HOS cells, respectively. Anticancer agent 274 has relatively low toxicity to normal cells and can be used in the research of tumors such as osteosarcoma[1].

分子量

361.39

Formula

C21H19N3O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 274 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 274Anticancer agent274Anticancer agent-274Drug DerivativeDrug derivativeSaOS-2MNNG-HOShOBInhibitorinhibitorinhibit

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目录号：
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