2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 47

Anticancer agent 47 (compound 4j) 是一种有效的抗癌剂。Anticancer agent 47 显示出抗增殖活性。Anticancer agent 47 诱导细胞凋亡 (apoptosis) 和细胞周期停滞在 G0/G1 期。Anticancer agent 47 在体内显示出抗肿瘤活性。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Anticancer agent 47 Chemical Structure

Anticancer agent 47 Chemical Structure

CAS No. : 2461795-23-1

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Anticancer agent 47 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 47 (compound 4j) is a potent anticancer agent. Anticancer agent 47 shows antiproliferative activities. Anticancer agent 47 induces apoptosis and cell cycle arrest at G0/G1 phase. Anticancer agent 47 shows shows antitumor activities in vivo[1].

体外研究
(In Vitro)

Anticancer agent 47 (compound 4j) shows antiproliferative activities with IC50s of 1.6, 0.72, 7.07 µM for HepG2, A549, H596 cells, respectively[1].
Anticancer agent 47 (0.8, 1.6, 3.2 µM; 24 h) induces apoptosis and cell cycle arrest at G0/G1 phase[1].
Anticancer agent 47 (5 µM; 5h) significantly increases ROS production[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 47 相关抗体:

Apoptosis Analysis[1]

Cell Line: HepG2, H596 cells
Concentration: 0.8, 1.6, 3.2 µM
Incubation Time: 24 h
Result: Induced apoptosis with the apoptotic cell rates were 14.23, 20.47 and 27.66% at 0.8, 1.6, 3.2 µM in HepG2 cell, respectively.

Cell Cycle Analysis[1]

Cell Line: HepG2 cells
Concentration: 0.8, 1.6, 3.2 µM
Incubation Time: 24 h
Result: Showed 48.54%, 49.60% and 53.00% cells were at G0/G1 phase at 0.6, 1.2 and 2.4 µM, respectively.
体内研究
(In Vivo)

Anticancer agent 47 (20 mg/kg; i.v.; once every 2 days for 19 days) shows antitumor activities[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: BALB/c nude mice (HepG2 xenografts)[1]
Dosage: 20 mg/kg
Administration: I.v.; once every 2 days for 19 days
Result: Effectively inhibited tumor growth with the 58.7% tumor inhibition rate.
分子量

366.39

Formula

C19H14N2O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 47 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 472461795-23-1Anticancer agent47Anticancer agent-47ApoptosisantitumorHepG2 cellsROS productionapoptosisG0/G1 phaseHepG2 xenograftsInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Anticancer agent 47
目录号：
HY-146040
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z