2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 55

Anticancer Agent 是一种有效的抗癌剂。Anticancer Agent 以剂量依赖性方式降低细胞活力和细胞迁移来显示抗癌活性。Anticancer Agent 诱导细胞凋亡 (apoptosis)。Anticancer Agent 具有研究前列腺癌和乳腺癌的潜力。

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Anticancer agent 55 Chemical Structure

Anticancer agent 55 Chemical Structure

CAS No. : 2408800-91-7

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Anticancer agent 55 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Anticancer agent 55 is a potent anticancer agent. Anticancer agent 55 shows anticancer activity via reducing the cell viability and cell migration in a dose-dependent manner. Anticancer agent 55 induces apoptosis. Anticancer agent 55 has the potential for the research of prostate cancer and breast cancer[1].

体外研究
(In Vitro)

Anticancer agent 55 (compound 3h) (0-100 µM; 48 h) inhibits cell viability with IC50s of 1.18 µM and 1.95 µM for PC-3, MCF-7 cells, respectively[1].
Anticancer agent 55 (0, 1, 3, 10 µM; 24 h) inhibits cell migration of PC-3 cells and MCF-7 cells in a dose-dependent manner[1].
Anticancer agent 55 (0, 1, 3, 10 µM; 12, 24 h) induces apoptosis by increases the caspase-3 activity and cleaved PARP levels[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 55 相关抗体:

Cell Viability Assay[1]

Cell Line: PC-3, MCF-7 cells
Concentration: 0-100 µM
Incubation Time: 48 h
Result: Significantly inhibited cell viability of PC-3, MCF-7 cells with IC50s of 1.18 µM and 1.95 µM, respectively.

Apoptosis Analysis[1]

Cell Line: PC-3, MCF-7 cells
Concentration: 0, 1, 3, 10 µM
Incubation Time: PC-3 for 12 h; MCF-7 for 24 h
Result: Induced apoptosis by increased the caspase-3 activity in a concentration-dependent manner.

Western Blot Analysis[1]

Cell Line: PC-3, MCF-7 cells
Concentration: 0, 1, 3, 10 µM
Incubation Time: PC-3 for 12 h; MCF-7 for 24 h
Result: Increased cleaved PARP levels in a dose-dependent manner in PC-3 and MCF-7 cells.
分子量

596.28

Formula

C28H21Br2FN2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 55 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 552408800-91-7Anticancer agent55Anticancer agent-55ApoptosisPC-3MCF-7 cellsmigrationapoptosisanticancercaspase-3cleaved PARPprostate cancerbreast cancerInhibitorinhibitorinhibit

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