2. Anti-infection
  3. Parasite
  4. Antimalarial agent 23

Antimalarial agent 23 是一种抗疟药 (antimalarial) 苯并咪唑，对 PfNF54 和 PfK1 的 IC50 值分别为 0.08 μM 和 0.10 μM。Antimalarial agent 23 具有有效的 β-血红素抑制活性。Antimalarial agent 23 不直接抑制血红素向疟原虫色素的转化。

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Antimalarial agent 23 Chemical Structure

Antimalarial agent 23 Chemical Structure

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Antimalarial agent 23 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Antimalarial agent 23 is an antimalarial benzimidazole with IC50s of 0.08 μM and 0.10 μM for PfNF54 and PfK1, respectively. Antimalarial agent 23 has potent β-hematin inhibition activity. Antimalarial agent 23 does not directly inhibit the conversion of heme to hemozoin[1].

体外研究
(In Vitro)

Antimalarial agent 23 (化合物 14) 对 CHO 细胞具有细胞毒性，IC50 为 37.3 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antimalarial agent 23 相关抗体:
分子量

489.92

Formula

C24H23ClF3N5O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antimalarial agent 23 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimalarial agent 23Antimalarial agent23Antimalarial agent-23ParasiteAntimalarialbenzimidazolePfNF54PfK1β-hematinhemehemozoinInhibitorinhibitorinhibit

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