2. Anti-infection
  3. Bacterial
  4. Antimycobacterial agent-12

Antimycobacterial agent-12 (Compound Ec42) 是一种 Platensimycin (HY-127146) 衍生物，是一种双功能 KasA 和 KasB 抑制剂。Antimycobacterial agent-12 对 Staphylococcus aureus ATCC 29213、Mycobacterium smegmatis 及其 Isoniazid (HY-B0329) 耐药菌株的 MIC 分别为 2 μg/mL、2 μg/mL 和 4 μg/mL。Antimycobacterial agent-12 在 M. smegmatis 感染小鼠模型中表现出优异的抗分枝杆菌活性。Antimycobacterial agent-12 可用于结核病研究。

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Antimycobacterial agent-12

Antimycobacterial agent-12 Chemical Structure

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Antimycobacterial agent-12 相关抗体

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  • 生物活性

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生物活性

Antimycobacterial agent-12 (Compound Ec42), a derivative of Platensimycin (HY-127146), is a dual-functional inhibitor KasA and KasB. Antimycobacterial agent-12 has antibacterial activity with a MICs of 2, 2 and 4 μg/mL against Staphylococcus aureus ATCC 29213, Mycobacterium smegmatis and its Isoniazid (HY-B0329)-resistant strain, respectively. Antimycobacterial agent-12 has a superior antimycobacterial activity in M. smegmatis-infected mouse models. Antimycobacterial agent-12 can be used for tuberculosis research[1].

分子量

625.73

Formula

C36H35NO7S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antimycobacterial agent-12 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimycobacterial agent-12Antimycobacterial agent12Antimycobacterial agent 12BacterialPlatensimycinKasAKasBStaphylococcus aureusMycobacterium smegmatisAntimycobacterialM. smegmatis-infected mouse modelsTuberculosisInhibitorinhibitorinhibit

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