2. GPCR/G Protein
  3. Protease Activated Receptor (PAR)
  4. APC 366 TFA

APC 366 (TFA) 是一种不可逆的肥大细胞胰蛋白酶抑制剂。APC 366 (TFA) 可用于过敏性疾病的研究。

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APC 366 TFA Chemical Structure

APC 366 TFA Chemical Structure

CAS No. : 2421110-28-1

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规格 价格 是否有货
1 mg ￥1100
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APC 366 TFA 的其他形式现货产品:

Customer Review

Other Forms of APC 366 TFA:

APC 366 TFA 相关抗体

Top Publications Citing Use of Products

查看 Protease Activated Receptor (PAR) 亚型特异性产品:

查看所有亚型
PAR1 PAR2 PAR4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases[1].

IC50 & Target

mast cell tryptase[1]
体内研究
(In Vivo)

APC 366 (TFA) (5 mg/kg/0.1 ml; s.c.) reduces the eosinophil recruitment induced by PAR-2 activating peptide[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male BALB/c mice (18–25 g)[1]
Dosage: 5 mg/kg/0.1 ml
Administration: S.c.
Result: Reduced the eosinophil recruitment induced by PAR-2 activating peptide.
分子量

554.52

Formula

C24H29F3N6O6
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料

纯度: ≥99.0%

COA (168 KB)

产品使用指南 (1538 KB)
参考文献

APC 366 TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

APC 3662421110-28-1APC366APC-366Protease Activated Receptor (PAR)Thrombin receptorsirreversiblemasttryptaseallergiceosinophilrecruitmentPAR-2Inhibitorinhibitorinhibit

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产品名称：
APC 366 TFA
目录号：
HY-105999B
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