1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Atorvastatin Epoxy Tetrahydrofuran Impurity

Atorvastatin Epoxy Tetrahydrofuran Impurity  (Synonyms: 阿托伐他汀钙杂质Atorvastatin Epoxy Tetrahydrofuran Impurity)

目录号: HY-136185
产品使用指南

Atorvastatin Epoxy Tetrahydrofuran Impurity 是阿托伐他汀 (Atorvastatin;HY-B0589) 氧化降解产物的一种杂质。Atorvastatin 是一种具有口服活性的 HMG-CoA 还原酶抑制剂,具有有效降低血脂的能力。

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Atorvastatin Epoxy Tetrahydrofuran Impurity Chemical Structure

Atorvastatin Epoxy Tetrahydrofuran Impurity Chemical Structure

CAS No. : 873950-19-7

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1 mg ¥12450
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B0589)[1]. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.

体外研究
(In Vitro)

Atorvastatin treatment decreases apoptosis of myocardial cells by down-regulating GRP78, caspase-12 and CHOP expression in myocardial cells after myocardial infarction, and the endoplasmic reticulum (ER) stress is activated in response to heart failure and angiotensin II (Ang II) stimulation.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

449.47

Formula

C26H24FNO5

CAS 号
中文名称

阿托伐他汀钙杂质Atorvastatin Epoxy Tetrahydrofuran Impurity

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Atorvastatin Epoxy Tetrahydrofuran Impurity 相关分类

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产品名称:
Atorvastatin Epoxy Tetrahydrofuran Impurity
目录号:
HY-136185
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