1. GPCR/G Protein Neuronal Signaling
  2. Cholecystokinin Receptor
  3. BBL454

BBL454 (Compound 43) 是一种胆囊收缩素 2B (CCK2B) 受体激动剂。BBL454 在大鼠模型中诱导多动症并改善记忆力,但对外周 CCK2 受体的活性较弱,且无致焦虑活性。BBL454 在麻醉大鼠模型中可增加胃酸分泌。BBL454 可用于糖尿病研究。

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BBL454

BBL454 Chemical Structure

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查看 Cholecystokinin Receptor 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BBL454 (Compound 43) is a Cholecystokinin 2B (CCK2B) receptor agonist. BBL454 induces hyperactivity and improves memory in rat models while it has weak activity on the peripheral CCK2 receptor and no anxiogenic activity. BBL454 increases gastric acid output in anesthetised rat models. BBL454 can be used for diabetes research[1][2].

IC50 & Target[1]

CCKBR

 

分子量

746.89

Formula

C40H54N6O8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
BBL454
目录号:
HY-177509
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