2. Metabolic Enzyme/Protease
  3. Serpin
  4. Belcesiran sodium

Belcesiran sodium  (Synonyms: DCR-S1459 sodium)

目录号: HY-177619A
产品使用指南 技术支持

Belcesiran 是一种小干扰 RNA（siRNA），它是一种α1 抗胰蛋白酶（A1AT）抑制剂，其作用机制是促使肝脏合成 A1AT 蛋白并将其释放到血液中。

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RNA, (Am-sp-Am-(2'-deoxy-2'-fluoro)A-Cm-Cm-Cm-Um-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-Um-Cm-Um-(2'-deoxy-2'-fluoro)U-Am-Am-Am-Gm-Cm-Am-Gm-Cm-Cm-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]G-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-Gm-Gm-Cm-Um-Gm-Cm), complex with RNA ([1-de-β-D-ribofuranosyl-1-[(2R,3R,4S,5S)-tetrahydro-4-hydroxy-5-[(hydroxymethoxyphosphinyl)methoxy]-3-methoxy-2-furanyl]]U-(4'→5')-sp-(2'-deoxy-2'-fluoro)U-sp-(2'-deoxy-2'-fluoro)U-sp-Am-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Am-Gm-Am-Cm-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)G-Gm-Um-(2'-deoxy-2'-fluoro)U-Um-sp-Gm-sp-Gm) (1:1), sodium salt

Belcesiran sodium Chemical Structure

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100 mg   询价  
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Customer Review

Belcesiran sodium 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Belcesiran is an alpha 1 antitrypsin (A1AT) inhibitor that acts by allowing the liver to synthesise the A1AT protein and pass it into the bloodstream.

分子量

22308.20

Formula

C666H819O417N231Na58F15P57S6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Belcesiran sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BelcesiranDCR-S1459SerpinSerine protease inhibitors (Serpins)Inhibitorinhibitorinhibit

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目录号：
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