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  2. Biotin-β-Amyloid (17-40)

Biotin-β-Amyloid (17-40) 

目录号: HY-P2551
产品使用指南

Biotin-β-Amyloid (17-40) 是一种 N 端标记的生物素化淀粉样蛋白 β-Amyloid (17-40) 肽。β-Amyloid (17-40) 是 Aβ 蛋白的 24 个残基片段,由淀粉样前体蛋白 (APP) 的翻译加工后而成。

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Biotin-β-Amyloid (17-40) Chemical Structure

Biotin-β-Amyloid (17-40) Chemical Structure

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Description

Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP)[1].

In Vitro

β-Amyloid (17-40) (5-10 μM) increases the rate of Aβ (1-40) aggregation more than addition of equivalent amounts of β-Amyloid (17-28), because it facilitates aggregation of Aβ40 through two different mechanisms, one promoted by residues 17-21 and the second by residues 30-35[1]. Biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. Biotin can be used for qualitative and quantitative detection, labelling or immobilisation.

Molecular Weight

2619.20

Formula

C₁₂₀H₁₉₂N₂₈O₃₃S₂

Sequence Shortening

Biotin-LVFFAEDVGSNKGAIIGLMVGGVV

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Biotin-β-Amyloid (17-40)OthersaggregationAβ40BiotinylatedInhibitorinhibitorinhibit

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产品名称:
Biotin-β-Amyloid (17-40)
目录号:
HY-P2551
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