Bischloroanthrabenzoxocinone  (Synonyms: (-)-BABX)

Bischloroanthrabenzoxocinone is a potent Type II fatty acid synthesis (FASII) inhibitor. Bischloroanthrabenzoxocinone inhibits fatty acid synthesis. Bischloroanthrabenzoxocinone shows antibacterial activities and inhibits phospholipid, DNA, RNA, protein, and cell wall synthesis^[1].

Bischloroanthrabenzoxocinone (0.01-333 µg/mL) 抑制脂肪酸合成，对 Staphylococcus aureus 和 Escherichia coli 的 IC₅₀ 值分别为 11.4、35.3 µg/mL^[1].
Bischloroanthrabenzoxocinone (0-250 µg/mL) 显示出抗菌活性，对 Staphylococcus aureus 和 野生型 Escherichia coli 的 MIC 值分别为 0.2、>250 µg/mL ^[1].
Iscloroanthrabenzoxocinone 抑制磷脂合成，IC₅₀ 值为 0.21 μg/ml，它还抑制 Staphylococcus aureus 和 Escherichia coli 中的 DNA、RNA、蛋白质和细胞壁合成^[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

543.39

C₂₈H₂₄Cl₂O₇

866022-28-8

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Kodali S, et al. Determination of selectivity and efficacy of fatty acid synthesis inhibitors. J Biol Chem. 2005 Jan 14;280(2):1669-77.  [Content Brief]