1. Peptides
  2. Brain Natriuretic Peptide-45, rat TFA

Brain Natriuretic Peptide-45, rat TFA  (Synonyms: BNP-45, rat TFA)

目录号: HY-P1573A
产品使用指南

Brain Natriuretic Peptide-45, rat TFA (BNP-45, rat TFA) 是一种从大鼠心脏中分离出来的大鼠脑利钠肽的循环形式,具有强大的降压和利钠功效。

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Brain Natriuretic Peptide-45, rat TFA Chemical Structure

Brain Natriuretic Peptide-45, rat TFA Chemical Structure

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Other Forms of Brain Natriuretic Peptide-45, rat TFA:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Brain Natriuretic Peptide-45, rat TFA (BNP-45, rat TFA) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency[1].

体内研究
(In Vivo)

Brain Natriuretic Peptide-45, rat (0.1, 0.2, 0.5, 1.0 and 2.0 nmol/kg, i.v.) shows potent natriuretic and hypotensive activities in anesthetized spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). Brain Natriuretic Peptide-45, rat with high concentration decreases blood pressure in SHR. But WKY is more susceptible than SHR to BNP-45 for diuresis, natriuresis and urinary cGMP excretion. In addition, high dose of Brain Natriuretic Peptide-45, rat cuases prolonged lowering of blood pressure and urinary cGMP excretion in WKY[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

5040.67 (free acid)

Formula

C213H349N71O65S3.xC2HF3O2

Sequence

Ser-Gln-Asp-Ser-Ala-Phe-Arg-Ile-Gln-Glu-Arg-Leu-Arg-Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys-Phe-Gly-Gln-Lys-Ile-Asp-Arg-Ile-Gly-Ala-Val-Ser-Arg-Leu-Gly-Cys-Asp-Gly-Leu-Arg-Leu-Phe(Disulfide bridge: Cys23-Cys39)

Sequence Shortening

SQDSAFRIQERLRNSKMAHSSSCFGQKIDRIGAVSRLGCDGLRLF(Disulfide bridge: Cys23-Cys39)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Brain Natriuretic Peptide-45, rat TFA
目录号:
HY-P1573A
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