CY5.5-COOH chloride  (Synonyms: Cyanine 5.5 carboxylic acid chloride)

Cy5.5-COOH (Cyanine 5.5 carboxylic acid) chloride is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH chloride possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH chloride can be used for bioimaging and disease diagnosis^[1].

Cy5.5-COOH chloride 标记聚丙烯 (PP) 微塑料用于生物成像的简要步骤^[1]:
1. 标记 PP 微塑料: 将 PP 微塑料与四氢呋喃、蒸馏水混合，加入 Cy5.5-COOH chloride 的 DMSO 溶液，搅拌 4 天后过滤、洗涤并干燥。
2. 验证标记效果: 通过 SEM、PSA 确认粒径形态，FT-IR 验证化学结构，IVIS 成像检测荧光强度。
3. 稳定性测试: 在玉米油中测试荧光稳定性，模拟胃肠液验证消化稳定性。
4. 生物分布研究: 小鼠口服 Cy-PP 后，通过 IVIS 实时监测不同时间点的体内分布，24 小时后检测器官及粪便中的荧光信号。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

619.23

Cyanine 5.5 carboxylic acid chloride

C₄₀H₄₃ClN₂O₂

2410537-32-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Sijoon Lee, et al. Toxicity and Biodistribution of Fragmented Polypropylene Microplastics in ICR Mice. Int J Mol Sci. 2023 May 9;24(10):8463.  [Content Brief]