2. Metabolic Enzyme/Protease
  3. E1/E2/E3 Enzyme
  4. DCN1-UBC12-IN-2

DCN1-UBC12-IN-2 是一种有效且特异性的 DCN1-UBC12 抑制剂(IC50= 9.55 nM)。DCN1-UBC12-IN-2 可特异性靶向 DCN1-UBC12 相互作用并缓解 Ang II 诱导的心脏成纤维细胞活化。

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DCN1-UBC12-IN-2 Chemical Structure

DCN1-UBC12-IN-2 Chemical Structure

CAS No. : 2374827-47-9

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DCN1-UBC12-IN-2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DCN1-UBC12-IN-2 is a potent and specific DCN1-UBC12 inhibitor (IC50=9.55 nM). DCN1-UBC12-IN-2 could specifically target DCN1-UBC12 interaction and relieve Ang II-induced cardiac fibroblast activation[1].

体外研究
(In Vitro)

DCN1-UBC12-IN-2 (DN-2) possesses relatively low cytotoxicity toward cardiac fibroblasts (CFs) with an IC50 of 27.34 μM for 24 h.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DCN1-UBC12-IN-2 相关抗体:
分子量

542.03

Formula

C23H20ClN7O3S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DCN1-UBC12-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DCN1-UBC12-IN-22374827-47-9E1/E2/E3 EnzymeE1 activating enzymeE2 conjugating enzymeE3 ligating enzymeUbiquitin activating enzymeUbiquitin conjugating enzymeUbiquitin ligaseanticardiac fibrotic effectselectivelow cytotoxicityDCN1-UBC12 interactionInhibitorinhibitorinhibit

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