1. Neuronal Signaling
  2. Amyloid-β
  3. Dehydro nicardipine

Dehydro nicardipine 是 Nicardipine (HY-12515) 的二氢吡啶类代谢产物,属于二氢吡啶类化合物。Dehydro nicardipine 可选择性抑制 Aβ 单体聚集,特异性调控 Aβ 可溶性聚集体的延伸和结合,改变 Aβ 聚集体的形态,抑制聚集体长度增长。Dehydro nicardipine 可用于阿尔茨海默病 (AD) 的研究。

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Dehydro nicardipine Chemical Structure

Dehydro nicardipine Chemical Structure

CAS No. : 59875-58-0

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  • 生物活性

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生物活性

Dehydro nicardipine is a dihydropyridine metabolite of Nicardipine (HY-12515) and belongs to the dihydropyridine class of compounds. Dehydro nicardipine can selectively inhibit the aggregation of Aβ monomers, specifically regulate the extension and binding of Aβ soluble aggregates, change the morphology of Aβ aggregates, and inhibit the growth of aggregate length. Dehydro nicardipine can be used in the study of Alzheimer's disease (AD)[1].

分子量

477.51

Formula

C26H27N3O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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Dehydro nicardipine 相关分类

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产品名称:
Dehydro nicardipine
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HY-W721681
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