2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. DMPEN

DMPEN  (Synonyms: NSC 682691; 4-Demethylpenclomedine)

目录号: HY-13533
产品使用指南 技术支持

DMPEN (NSC 682691) (4-Demethylpenclomedine) 是一种 Penclomedine (HY-106401) 烷化代谢物。DMPEN 具有抗肿瘤活性。DMPEN 在大鼠小脑模型中不会诱导 Purkinje 细胞丢失，且无显著的小脑神经毒性。DMPEN 可用于乳腺癌和脑癌等癌症的研究。

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DMPEN

DMPEN Chemical Structure

CAS No. : 176046-79-0

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DMPEN 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DMPEN (NSC 682691) (4-Demethylpenclomedine) is an alkylating metabolite of Penclomedine (HY-106401). DMPEN has an antitumor activity. DMPEN does not induce Purkinje cells loss with no significant neurocerebellar toxicity in rat cerebellum models. DMPEN can be used for cancers like breast and brain cancer research[1].

分子量

311.38

Formula

C7H4Cl5NO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DMPEN 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DMPEN176046-79-0NSC 682691 4-DemethylpenclomedineNSC682691NSC-682691Drug MetabolitePenclomedineAlkylating metabolitePurkinje cellsNeurocerebellar toxicityAntitumorBreast cancerBrain cancerInhibitorinhibitorinhibit

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