1. Metabolic Enzyme/Protease
  2. MetAP
  3. Ebelactone A

Ebelactone A 是一种霉菌酸 β-内酯,对酯酶 (esterase),脂肪酶 (lipase),fMet 氨肽酶 (fMet AP) 和 PNBase 具有抑制活性,IC50 分别为 56,3,8 和 7.5 μM。Ebelactone A 抑制角质酶 (cutinase) 活性,具有植物保护作用。

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Ebelactone A Chemical Structure

Ebelactone A Chemical Structure

CAS No. : 76808-16-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ebelactone A is a mycolic acid β-lactone, which exhibits inhibitory activity for esterase, lipase, fMet aminopeptidase (fMet AP) and PNBase, with IC50s of 56, 3, 8 and 7.5 μM, respectively[1]. Ebelactone A inhibits cutinase, exhibits plants protective potency against Erysiphe graminis[2].

IC50 & Target

56 μM (esterase), 3 μM (lipase), 8 μM (fMet AP), 7.5 μM (PNBase)

体外研究
(In Vitro)

Ebelactone A (0.1-1 mM) 抑制大麦叶子上的发芽,AGT 形成和孢子集落形成[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

338.48

Formula

C20H34O4

CAS 号
结构分类
初始来源

actinomycetes

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Ebelactone A 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ebelactone A
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HY-126564
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