2. Metabolic Enzyme/Protease
  3. Mitochondrial Metabolism
  4. Elamipretide TFA

Elamipretide TFA  (Synonyms: MTP-131 TFA; RX-31 TFA; SS-31 TFA)

目录号: HY-P0125A
产品使用指南 技术支持

Elamipretide TFA (MTP-131 TFA; RX-31 TFA; SS-31 TFA) 是 Elamipretide (HY-P0125) 的TFA 盐形式。Elamipretide TFA 是一种线粒体靶向肽，可改善心肌梗死、改善肾功能并保护神经元免受炎症和氧化应激损伤。

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Elamipretide TFA

Elamipretide TFA Chemical Structure

CAS No. : 1606994-55-1

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规格 价格 是否有货
1 mg ￥500
询问价格 & 货期
5 mg ￥1200
询问价格 & 货期
10 mg ￥2000
询问价格 & 货期

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Elamipretide TFA 的其他形式现货产品:

Customer Review

Other Forms of Elamipretide TFA:

Elamipretide TFA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Elamipretide TFA (MTP-131 TFA; RX-31 TFA; SS-31 TFA) is the TFA salt form of Elamipretide (HY-P0125). Elamipretide TFA is a mitochondria-targeting peptide, which ameliorates myocardial infarction, improves the renal function and protects neurons form inflammatory and oxidative stress injury[1][2].

IC50 & Target

Cardiolipin peroxidase[1]
体内研究
(In Vivo)

Elamipretide TFA (5 mg/kg, i.p., once daily for 3 days) 具有神经保护作用，保护海马体免受线粒体功能障碍的影响，并减轻Lipopolysaccharide (HY-D1056) 诱导的 C57BL/6 小鼠认知障碍模型中的氧化应激和炎症反应[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: LPS-induced cognitive impairment in C57BL/6 mice model[1]
Dosage: 5 mg/kg
Administration: i.p., once daily for 3 days
Result: Maintained the mitochondrial function, ROS and MDA levels, and SOD activity.
Inhibited neural cell apoptosis in hippocampus, enhanced the hippocampal BDNF pathway and synaptic structural complexity.
Clinical Trial
分子量

753.81

Formula

C34H50F3N9O7
CAS 号
性状

固体

Sequence

{d-Arg}-{Dmt}-Lys-Phe-NH2
Sequence Shortening

{d-Arg}-{Dmt}-KF-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

Elamipretide TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Elamipretide1606994-55-1MTP-131RX-31SS-31MTP131MTP 131RX31RX 31SS31SS 31Mitochondrial Metabolismheart failureC57BL/6 miceAlzheimer’s diseaseParkinson’s disease,Inhibitorinhibitorinhibit

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目录号：
HY-P0125A
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