1. Protein Tyrosine Kinase/RTK
  2. FGFR
  3. FGFR1 activator-1

FGFR1 activator-1 (Compound I-1) 是一种 FGFR1 激活剂,其 EC50 为 0.88 μM。FGFR1 activator-1 通过激活 FGFR1 及其下游 ERK 1/2 来促进细胞增殖。FGFR1 activator-1 可用于组织修复和伤口愈合相关疾病 (如牛皮癣和湿疹) 研究。

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FGFR1 activator-1

FGFR1 activator-1 Chemical Structure

CAS No. : 352513-86-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FGFR1 activator-1 (Compound I-1) is a FGFR1 activator with an EC50 of 0.88  μM. FGFR1 activator-1 enhances cell proliferation through activating FGFR1 and its downstream ERK 1/2. FGFR1 activator-1 can be used for tissue repair and wound healing related diseases like psoriasis and eczema research[1].

IC50 & Target[1]

FGFR1

0.88 μM (EC50)

分子量

708.78

Formula

C32H40N18O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

FGFR1 activator-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
FGFR1 activator-1
目录号:
HY-176862
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