2. Gene
  3. F2rl3 - F2R like thrombin or trypsin receptor 3 Gene

F2rl3 - F2R like thrombin or trypsin receptor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：F2 R 样凝血酶或胰蛋白酶受体 3

种属: Rattus norvegicus

同用名: PAR4

基因 ID: 116498 | 基因类型: protein coding

关于 F2rl3

Primary_assembly 16: 17,117,441-17,119,472 reverse strand.mRatBN7.2:CM026989.1

This gene has 1 transcript (splice variant), 194 orthologues, 14 paralogues and is associated with 3 phenotypes. Biased expression in Spleen (RPKM 9.7), Thymus (RPKM 7.4) and 8 other tissues.

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性。预计参与Rho蛋白信号转导的正调控；参与磷脂酶C激活G蛋白偶联信号通路的细胞溶质钙离子浓度的正向调节；正调节螯合钙离子释放到胞质溶胶中。预测位于质膜中。预计是质膜的组成部分。与人 F2RL3 同源（F2R 像凝血酶或胰蛋白酶受体 3）。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction; positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway; and positive regulation of release of sequestered calcium ion into cytosol. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human F2RL3 (F2R like Thrombin or trypsin receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

F2rl3 基因产物(1)

mRNA Protein Name
NM_053808.1 NP_446260.1 proteinase-activated receptor 4

F2rl3 蛋白结构

7tmA_PAR4

7tmA_PAR4: cd15372 (79 - 106)

7tmA_PAR4

7tmA_PAR4: cd15372 (79 - 352)

7tmA_PAR4

7tmA_PAR4: cd15372 (112 - 137)

7tmA_PAR4

7tmA_PAR4: cd15372 (150 - 180)

7tmA_PAR4

7tmA_PAR4: cd15372 (192 - 214)

7tmA_PAR4

7tmA_PAR4: cd15372 (242 - 271)

7tmA_PAR4

7tmA_PAR4: cd15372 (277 - 307)

7tmA_PAR4

7tmA_PAR4: cd15372 (320 - 345)

  • 0
  • 100
  • 200
  • 300
  • 386 a.a.
蛋白主名 其他名称

proteinase-activated receptor 4

F2R like thrombin/trypsin receptor 3

PAR-4

coagulation factor II (thrombin) receptor-like 3

coagulation factor II receptor-like 3

protease-activated receptor 4

thrombin receptor-like 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04640 F2RL3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04641 F2rl3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04642 F2rl3 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F2rl3 NCBI NCBI:9002
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