2. Gene
  3. Atf3 - activating transcription factor 3 Gene

Atf3 - activating transcription factor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: LRG-21

基因 ID: 11910 | 基因类型: protein coding

关于 Atf3

功能概要

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of ERK1 and ERK2 cascade; and regulation of gene expression. Acts upstream of or within gluconeogenesis; negative regulation of transcription, DNA-templated; and skeletal muscle cell differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and limb long bone. Orthologous to human ATF3 (activating transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Atf3 基因产物(1)

mRNA Protein Name
NM_007498.3 NP_031524.2 cyclic AMP-dependent transcription factor ATF-3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
11916968 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
16644691 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
16644691 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to amino acid starvation IMP
IMP: 通过突变表型推断
14729979 MGI
involved in endoplasmic reticulum unfolded protein response IMP
IMP: 通过突变表型推断
14729979 MGI
acts upstream of or within gluconeogenesis IDA
IDA: 通过直接分析推断
11916968 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11916968 MGI
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
22053207 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16644691 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
14729979 MGI
involved in positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
24939851 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
22147266 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
14729979 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cyclic AMP-dependent transcription factor ATF-3

cAMP-dependent transcription factor ATF-3

transcription factor LRG-21

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-151923 ATF3 inducer 1 Inhibitor 99.61% 否
HY-153347 JY-2 99.75% 否
HY-12756A E6446 dihydrochloride 99.96% 否
HY-W011927 4,4'-Sulfonyldiphenol 99.81% 否
HY-12756 E6446 98.78% 否
HY-162384 EPIC-0628 Inhibitor 98.93% 否
HY-RS01129 ATF3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W011927S 4,4'-Sulfonyldiphenol-d8 98.88% 否
HY-163319 NCA029 98.24% 否
HY-155158 Anticancer agent 147 Inducer / 否
HY-175032 ATF3-IN-1 / 否
HY-RS16909 Atf3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23351 Atf3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atf3 NCBI NCBI:467
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