2. Gene
  3. Fos - FBJ osteosarcoma oncogene Gene

Fos - FBJ osteosarcoma oncogene Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: cFos; c-fos; D12Rfj1

基因 ID: 14281 | 基因类型: protein coding

关于 Fos

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Acts upstream of or within several processes, including positive regulation of osteoclast differentiation; response to muscle stretch; and skeletal muscle cell differentiation. Located in endoplasmic reticulum and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and integumental system. Orthologous to human FOS (Fos proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Fos 基因产物(1)

mRNA Protein Name
NM_010234.3 NP_034364.1 protein c-Fos
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12486129 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
11925568 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
11925568 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
12220541 MGI
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
11925568 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11925568 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
20442316 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
2138707 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to calcium ion IDA
IDA: 通过直接分析推断
19365557 MGI
acts upstream of or within cellular response to stimulus IMP
IMP: 通过突变表型推断
9294610 MGI
acts upstream of or within nervous system development IMP
IMP: 通过突变表型推断
11925568 MGI
acts upstream of osteoclast differentiation IDA
IDA: 通过直接分析推断
23395171 MGI
acts upstream of or within positive regulation of osteoclast differentiation IDA
IDA: 通过直接分析推断
23395171 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
9294610 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
11925568 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12220541 MGI
acts upstream of or within regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
11925568 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
22284419 MGI
acts upstream of or within response to muscle stretch IDA
IDA: 通过直接分析推断
20442316 MGI
acts upstream of or within response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
9098922 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
22147266 MGI
acts upstream of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
9294610 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
26475860 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
26475860 MGI
located in nucleus IDA
IDA: 通过直接分析推断
7595148 MGI
part of transcription factor AP-1 complex IPI
IPI: 通过物理相互作用推断
1631061 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
12943993 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein c-Fos

cellular oncogene fos

proto-oncogene c-Fos

proto-oncogene protein c-fos

transcription factor AP-1 subunit c-Fos

相关产品

Approval
生物活性分子 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-113756A Latanoprost acid Inhibitor 99.62% 否
HY-A0116A Trandolaprilate hydrate Inhibitor 97.30% 否
HY-A0116 Trandolaprilate Inhibitor / 否
Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-12270 T-5224 Inhibitor 99.59% Phase 2
HY-100426A Osemozotan hydrochloride Agonist / Phase 2
HY-113726 Nerisopam Agonist / Phase 1
Pre-clinical Phase
生物活性分子 (36)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10408 Candidalysin Activator 99.38% 否
HY-N2577 1F-Fructofuranosylnystose 99.87% 否
HY-N2119 Sciadopitysin Inhibitor 99.0% 否
HY-N0231 Bavachalcone 99.90% 否
HY-N6837 Fructo-​oligosaccharide DP7/GF6 99.94% 否
HY-P10506 CMX-8933 Activator 99.82% 否
HY-107621 U0124 98.0% 否
HY-169021 JNK-1-IN-3 Inhibitor 98.44% 否
HY-N6836 Fructo-oligosaccharide DP8/GF7 99.76% 否
HY-P10927A BRP TFA Activator / 否
HY-100839 (RS)-(Tetrazol-5-yl)glycine Agonist 96.53% 否
HY-114753 Neboglamine Modulator / 否
HY-N6835 Fructo-oligosaccharide DP9/GF8 99.83% 否
HY-113443 12(S)-HPETE Activator / 否
HY-120306 HHL-6 Inhibitor / 否
HY-131721 14,15-EET-SI Activator / 否
HY-15026 ATB 429 / 否
HY-168482 NF-κB/MAPK-IN-2 Inhibitor / 否
HY-168895 c-Fos-IN-1 / 否
HY-169451 Cannabidiolic acid methyl ester Modulator / 否
HY-175007 RIPK1-IN-32 Inhibitor / 否
HY-176019 Methylcarbamyl PAF C-8 / 否
HY-A0116S1 Trandolaprilate-d6 / 否
HY-E70684 CDK5/p25NCK Recombinant Human Active Protein Kinase / 否
HY-E70685 CDK5/p35NCK Recombinant Human Active Protein Kinase / 否
HY-N11775 Eudebeiolide B / 否
HY-N3071 Picrasidine I / 否
HY-N6834 Fructo-​oligosaccharide DP10/GF9 98.0% 否
HY-N7008 Fructo-oligosaccharide DP11/GF10 / 否
HY-N7009 Fructo-oligosaccharide DP12/GF11 / 否
HY-P10927 BRP Activator 95.15% 否
HY-RS05032 FOS Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174682 Human FOS mRNA / 否
HY-B1606 Chlorothymol 99.70% 否
HY-RS16815 Fos Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23255 Fos Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fos NCBI NCBI:2353
Macaca fascicularis Fos NCBI NCBI:102143716
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