2. Gene
  3. Ide - insulin degrading enzyme Gene

Ide - insulin degrading enzyme Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 1300012G03Rik; 4833415K22Rik

基因 ID: 15925 | 基因类型: protein coding

关于 Ide

功能概要

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and peptide binding activity. Involved in Insulin catabolic process. Acts upstream of or within amyloid-beta clearance and response to oxidative stress. Located in extracellular exosome. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human IDE (Insulin degrading enzyme). [provided by Alliance of Genome Resources, Apr 2022]

Ide 基因产物(1)

mRNA Protein Name
NM_031156.4 NP_112419.4 insulin-degrading enzyme
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables endopeptidase activity IDA
IDA: 通过直接分析推断
27703010 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within amyloid-beta clearance IDA
IDA: 通过直接分析推断
26637123 MGI
involved in amyloid-beta clearance IMP
IMP: 通过突变表型推断
20876579 MGI
involved in insulin catabolic process IDA
IDA: 通过直接分析推断
27703010 MGI
involved in insulin catabolic process IMP
IMP: 通过突变表型推断
24847884 MGI
involved in insulin receptor recycling IDA
IDA: 通过直接分析推断
27703010 MGI
involved in protein catabolic process IMP
IMP: 通过突变表型推断
20876579 MGI
acts upstream of or within response to oxidative stress IDA
IDA: 通过直接分析推断
26637123 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in endosome lumen IDA
IDA: 通过直接分析推断
27703010 MGI
located in extracellular exosome IMP
IMP: 通过突变表型推断
20876579 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

insulin-degrading enzyme

insulin protease

insulinase

insulysin

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-101569 Darovasertib Inhibitor 99.18% Phase 2
Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100533 IDE1 98.51% 否
HY-N7135 Tropolone Inhibitor 99.93% 否
HY-110197 6bK TFA 99.35% 否
HY-100534 IDE 2 Agonist 99.00% 否
HY-117878 ML345 Inhibitor 99.37% 否
HY-169422 GSK4418959 Inhibitor 99.07% 否
HY-W157689 IDE-IN-2 Inhibitor 98.04% 否
HY-169422A GSK4418959 (enantiomer) 95.0% 否
HY-114611 BDM44768 / 否
HY-12655 IDE-IN-1 Inhibitor / 否
HY-143401 Hit 1 Activator / 否
HY-RS06526 IDE Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W616806 Sodium 6-oxo-3,6-dihydropurin-7-ide / 否
HY-Y0424AS Potassium 1,3-dioxoisoindolin-2-ide-15N / 否
HY-RS16920 Ide Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23363 Ide Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ide NCBI NCBI:3416
Canis familiaris Ide NCBI NCBI:477768
Macaca fascicularis Ide NCBI NCBI:102128252
Susscrofa domestica Ide NCBI
Rattus norvegicus Ide NCBI NCBI:25700
Macaca mulatta Ide NCBI NCBI:698640
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