2. Gene
  3. Lats1 - large tumor suppressor Gene

Lats1 - large tumor suppressor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 16798 | 基因类型: protein coding

关于 Lats1

功能概要

Predicted to enable several functions, including ATP binding activity; Estrogen receptor binding activity; and magnesium ion binding activity. Involved in hormone-mediated signaling pathway; negative regulation of protein localization to nucleus; and regulation of transforming growth factor beta receptor signaling pathway. Acts upstream of or within several processes, including hippo signaling; inner cell mass cell differentiation; and keratinocyte differentiation. Predicted to be located in cytoplasm and Cytoskeleton. Predicted to be active in spindle pole. Is expressed in acoustic ganglion; early conceptus; embryo; endolymphatic appendage; and otocyst. Orthologous to human LATS1 (large tumor suppressor kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Lats1 基因产物(1)

mRNA Protein Name
NM_010690.1 NP_034820.1 serine/threonine-protein kinase LATS1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21145499 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within hippo signaling IGI
IGI: 通过遗传相互作用推断
18369314 MGI
involved in hormone-mediated signaling pathway IDA
IDA: 通过直接分析推断
9988269 MGI
acts upstream of or within inner cell mass cell fate commitment IGI
IGI: 通过遗传相互作用推断
23824537 MGI
acts upstream of or within inner cell mass cellular morphogenesis IGI
IGI: 通过遗传相互作用推断
23824537 MGI
acts upstream of or within keratinocyte differentiation IGI
IGI: 通过遗传相互作用推断
18369314 MGI
involved in negative regulation of protein localization to nucleus IMP
IMP: 通过突变表型推断
21145499 MGI
acts upstream of or within protein localization IGI
IGI: 通过遗传相互作用推断
19289085 MGI
involved in regulation of transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
21145499 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein kinase LATS1

WARTS protein kinase

large tumor suppressor homolog 1

large tumor supressor, homolog 1

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-164401 QBS10072S / Phase 2
Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-138489 TRULI Modulator 99.98% 否
HY-108540 BCH Inducer 99.13% 否
HY-147082 GA-017 Activator 98.95% 否
HY-W011391 GPNA hydrochloride 99.91% 否
HY-139330 MGH-CP1 Inducer 99.56% 否
HY-W087830 L-p-Boronophenylalanine 99.79% 否
HY-120139 KMH-233 Inhibitor 99.75% 否
HY-147165 VT02956 Inhibitor 99.58% 否
HY-120139A (R)-KMH-233 Control / 否
HY-175247 DDO-4033 Agonist / 否
HY-175649 LATS1/2-IN-1 Inhibitor / 否
HY-RS07538 LATS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-147165A VT02956 hydrochloride Inhibitor / 否
HY-176886 LATS-IN-2 Inhibitor / 否
HY-RS17343 Lats1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23797 Lats1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lats1 NCBI NCBI:9113
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