2. Gene
  3. Ptprn - protein tyrosine phosphatase, receptor type, N Gene

Ptprn - protein tyrosine phosphatase, receptor type, N Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IA-2; mIA-A; R-PTP-N; PTP IA-2; mKIAA4064

基因 ID: 19275 | 基因类型: protein coding

关于 Ptprn

功能概要

Predicted to enable GTPase binding activity; spectrin binding activity; and ubiquitin-like protein Ligase binding activity. Involved in Insulin secretion involved in cellular response to glucose stimulus; luteinization; and positive regulation of type B pancreatic cell proliferation. Predicted to be located in several cellular components, including axon terminus; neuronal cell body; and secretory granule. Predicted to colocalize with Golgi apparatus; endosome; and plasma membrane. Is expressed in lens vesicle and nervous system. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human PTPRN (protein tyrosine Phosphatase receptor type N). [provided by Alliance of Genome Resources, Apr 2022]

Ptprn 基因产物(4)

mRNA Protein Name
NM_001359281.2 NP_001346210.1 receptor-type tyrosine-protein phosphatase-like N isoform 2
NM_001405067.1 NP_001391996.1 receptor-type tyrosine-protein phosphatase-like N isoform 3
NM_001405068.2 NP_001391997.1 receptor-type tyrosine-protein phosphatase-like N isoform 2
NM_008985.4 NP_033011.2 receptor-type tyrosine-protein phosphatase-like N isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12364328 MGI
NOT enables protein tyrosine phosphatase activity IDA
IDA: 通过直接分析推断
8878556 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
12031972 MGI
involved in luteinization IMP
IMP: 通过突变表型推断
16269463 MGI
involved in positive regulation of type B pancreatic cell proliferation IMP
IMP: 通过突变表型推断
18178618 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

receptor-type tyrosine-protein phosphatase-like N

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11444 PTPRN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS11445 PTPRN2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20475 Ptprn Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26983 Ptprn Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptprn NCBI NCBI:5798
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