2. Gene
  3. Onecut2 - one cut domain, family member 2 Gene

Onecut2 - one cut domain, family member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Oc2; OC-2; C730009D12

基因 ID: 225631 | 基因类型: protein coding

关于 Onecut2

功能概要

Enables DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including liver development; negative regulation of transforming growth factor beta receptor signaling pathway; and peripheral nervous system neuron development. Predicted to be located in actin Cytoskeleton and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; future brain; genitourinary system; gut; and retina. Orthologous to human ONECUT2 (one cut homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Onecut2 基因产物(1)

mRNA Protein Name
NM_194268.3 NP_919244.2 one cut domain family member 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
17400205 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11944891 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within anatomical structure morphogenesis IMP
IMP: 通过突变表型推断
16103213 MGI
acts upstream of or within cell fate commitment IGI
IGI: 通过遗传相互作用推断
16103213 MGI
acts upstream of cell migration IGI
IGI: 通过遗传相互作用推断
17936262 MGI
acts upstream of or within cilium assembly IMP
IMP: 通过突变表型推断
16472605 MGI
acts upstream of or within endocrine pancreas development IGI
IGI: 通过遗传相互作用推断
17400205 MGI
acts upstream of or within epithelial cell development IMP
IMP: 通过突变表型推断
16472605 MGI
acts upstream of or within liver development IGI
IGI: 通过遗传相互作用推断
17936262 MGI
acts upstream of mesenchymal stem cell migration IGI
IGI: 通过遗传相互作用推断
17936262 MGI
acts upstream of or within negative regulation of transforming growth factor beta receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
16103213 MGI
acts upstream of or within pancreas development IGI
IGI: 通过遗传相互作用推断
17400205 MGI
acts upstream of or within peripheral nervous system neuron development IMP
IMP: 通过突变表型推断
17698011 MGI
acts upstream of or within positive regulation of mesenchymal stem cell migration IGI
IGI: 通过遗传相互作用推断
17936262 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
17400205 MGI
acts upstream of or within regulation of cell-matrix adhesion IGI
IGI: 通过遗传相互作用推断
17936262 MGI
acts upstream of transforming growth factor beta receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
16103213 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

one cut domain family member 2

one cut homeobox 2

transcription factor ONECUT-2

transcription factor ONECUT2

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122611A CSRM617 hydrochloride 99.97% 否
HY-122611 CSRM617 / 否
HY-RS09786 ONECUT2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS19546 Onecut2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26042 Onecut2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Onecut2 NCBI NCBI:9480
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