PLA2G15 - phospholipase A2 group XV Gene

中文名称：磷脂酶 A2 第 XV 组

种属: Homo sapiens

同用名: ACS; LLPL; LPLA2; LYPLA3; GXVPLA2

关于 PLA2G15

功能概要

溶血磷脂酶是作用于生物膜以调节多功能溶血磷脂的酶。由该基因编码的蛋白质将溶血磷脂酰胆碱水解为甘油磷酰胆碱和游离脂肪酸。这种酶存在于血浆中，被认为与高密度脂蛋白有关。后来的一篇论文与该基因的功能相矛盾。它证明该基因编码溶酶体酶而不是溶血磷脂酶，并且具有钙非依赖性磷脂酶 A2 和转酰基酶活性。[RefSeq 提供，2008 年 7 月]

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This Enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal Enzyme instead of a lysophospholipase and has both calcium-independent Phospholipase A2 and transacylase activities. [provided by RefSeq, Jul 2008]