2. Gene
  3. Pah - phenylalanine hydroxylase Gene

Pah - phenylalanine hydroxylase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24616 | 基因类型: protein coding

关于 Pah

功能概要

Enables several functions, including identical protein binding activity; iron ion binding activity; and phenylalanine 4-monooxygenase activity. Involved in L-phenylalanine metabolic process; protein hydroxylation; and tyrosine biosynthetic process, by oxidation of phenylalanine. Human ortholog(s) of this gene implicated in intellectual disability and phenylketonuria. Orthologous to human PAH (phenylalanine hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]

Pah 基因产物(1)

mRNA Protein Name
NM_012619.2 NP_036751.2 phenylalanine-4-hydroxylase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables amino acid binding IDA
IDA: 通过直接分析推断
16953590 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
10331871 RGD
enables iron ion binding IDA
IDA: 通过直接分析推断
10331871 RGD
enables phenylalanine 4-monooxygenase activity IDA
IDA: 通过直接分析推断
10839989 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-phenylalanine metabolic process IDA
IDA: 通过直接分析推断
16953590 RGD
involved in protein hydroxylation IDA
IDA: 通过直接分析推断
16953590 RGD
involved in tyrosine biosynthetic process IDA
IDA: 通过直接分析推断
16953590 RGD
involved in tyrosine biosynthetic process, by oxidation of phenylalanine IDA
IDA: 通过直接分析推断
10839989 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phenylalanine-4-hydroxylase

phe-4-monooxygenase

相关产品

Approval
生物活性分子 (9)
目录号 产品名 作用方式
纯度 是否罕见病
HY-A0124A Sapropterin dihydrochloride 99.82% 是
HY-14184 Macitentan 99.87% 是
HY-P0012 Aviptadil Inhibitor 99.95% 否
HY-A0126A Epoprostenol sodium Inducer 98.03% 否
HY-11103 Sitaxsentan sodium Antagonist 98.83% 否
HY-P0012A Aviptadil acetate Inhibitor 99.87% 否
HY-109013 Sofpironium bromide Inhibitor 98.26% 否
HY-A0124 Sapropterin / 否
HY-A0126AR Epoprostenol sodium (Standard) / 否
Clinical Phase
生物活性分子 (6)
目录号 产品名 作用方式
纯度 Phase
HY-109112 Brilaroxazine 98.82% Phase 3
HY-109190 Seralutinib Inhibitor 99.94% Phase 2
HY-101124 Rodatristat ethyl Inhibitor ≥98.0% Phase 2
HY-129851 NTP42 Antagonist 98.58% Phase 1
HY-B1727 Phenanthrene 99.66% Phase 1
HY-170435 PDE5-IN-13 Inhibitor / Phase 1
Pre-clinical Phase
生物活性分子 (56)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W011845 DMBA Inducer 99.94% 否
HY-15425 PF-543 99.85% 否
HY-15425A PF-543 Citrate 99.47% 否
HY-103609 Pyrene 99.83% 否
HY-121107 Chrysene 99.81% 否
HY-W014075 1-Hydroxypyrene 99.84% 否
HY-161119 Drpitor1a Inhibitor 96.95% 否
HY-B1727S Phenanthrene-d10 99.46% 否
HY-W026772 Fluorene 99.35% 否
HY-108464A Phenamil methanesulfonate Inhibitor 98.1% 否
HY-153248 PBR28 99.44% 否
HY-W013053 Dibenz[a,h]anthracene Inducer ≥98.0% 否
HY-111450 CB7993113 Antagonist ≥98.0% 否
HY-W013570 Acenaphthylene 99.44% 否
HY-Y1771 2-Carboxybenzaldehyde 99.95% 否
HY-121107S Chrysene-d12 99.71% 否
HY-14184A Macitentan (n-butyl analogue) 99.35% 否
HY-128593 TPN171 Inhibitor 98.10% 否
HY-W014075S 1-Hydroxypyrene-d9 99.95% 否
HY-W026772S Fluorene-d10 ≥99.0% 否
HY-N11222 Nonanoylcarnitine 99.87% 否
HY-W026772S1 Fluorene-d8 / 否
HY-131973 PDE10A-IN-2 hydrochloride Inhibitor 98.43% 否
HY-14184S Macitentan-d4 98.03% 否
HY-170419 APJ receptor agonist 10 Agonist / 否
HY-P3242 Mad1 (6-21) 98.02% 否
HY-RS09979 PAH Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W013570S Acenaphthylene-d8 99.48% 否
HY-15425B PF-543 hydrochloride / 否
HY-115477 Brilaroxazine hydrochloride / 否
HY-121025 BUR1 Inhibitor 99.65% 否
HY-134620 Cyanine 5 NHS ester tetrafluoroborate / 否
HY-149492 Phosphatase-IN-1 Inhibitor / 否
HY-155737 ET receptor antagonist 1 Inhibitor / 否
HY-155738 ET receptor antagonist 2 Inhibitor / 否
HY-155739 ET receptor antagonist 3 Inhibitor / 否
HY-167849 Sofpironium tosylate Inhibitor / 否
HY-167906S Hexadecyl 2-((4-Nitrophenyl)thio)acetate-13C2 / 否
HY-168178 Hsp110-STAT3 PPI-IN-2 Inhibitor / 否
HY-170387 MRS8209 Antagonist / 否
HY-174416 Smurf1-IN-5 Inhibitor / 否
HY-23498 Benzo[k]fluoranthene / 否
HY-D1549 o-Pah / 否
HY-N10021 Benzo[e]pyrene / 否
HY-P3242A Mad1 (6-21) TFA / 否
HY-Q43097 Hsp110-STAT3 PPI-IN-1 Inhibitor / 否
HY-W777456 Phenanthrene-13C6 / 否
HY-W777458 Fluorene-13C6 / 否
HY-W778162 Phenanthrene-13C2 / 否
HY-108936 QCC374 Agonist / 否
HY-144856S1 Sapropterin-d3 / 否
HY-167906 Lunamarine / 否
HY-172508 Perylene dU phosphoramidite / 否
HY-33451 4-Dibenzofurancarboxylic acid / 否
HY-RS17018 Pah Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23461 Pah Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990733 Cibotercept Inhibitor 99.85% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pah NCBI NCBI:5053
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