2. Gene
  3. Pomc - proopiomelanocortin Gene

Pomc - proopiomelanocortin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pomc1; Pomc2; alphaMSH

基因 ID: 24664 | 基因类型: protein coding

关于 Pomc

功能概要

Predicted to enable hormone activity and Melanocortin Receptor binding activity. Predicted to be involved in several processes, including cortisol secretion; positive regulation of cAMP-mediated signaling; and regulation of gene expression. Predicted to act upstream of or within several processes, including calcium-mediated signaling; glucose homeostasis; and regulation of glycogen metabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in familial Mediterranean fever; obesity; and osteoarthritis. Orthologous to human POMC (proopiomelanocortin). [provided by Alliance of Genome Resources, Apr 2022]

Pomc 基因产物(1)

mRNA Protein Name
NM_139326.3 NP_647542.1 pro-opiomelanocortin precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to alcohol IEP
IEP: 通过表达模式推断
16925589 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
28511993 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
15316242 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pro-opiomelanocortin

alpha-melanocyte-stimulating hormone

corticotropin-lipotropin

pro-opiomelanocortin-alpha

proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)

proopiomelan

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P0252 α-MSH Agonist 99.98% Phase 2
HY-N6733 Aphidicolin 99.93% Phase 1
Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P0252A α-MSH TFA Agonist 98.54% 否
HY-P2281A Atrial natriuretic factor (1-28) (human, porcine) TFA 98.07% 否
HY-P1210A Lys-γ3-MSH(human) TFA 97.44% 否
HY-P1922 γ-2-MSH (41-58), amide Agonist 98.80% 否
HY-P2281 Atrial natriuretic factor (1-28) (human, porcine) / 否
HY-117787 TUG-905 Agonist / 否
HY-121859 RU28362 / 否
HY-P1210 Lys-γ3-MSH(human) Agonist / 否
HY-P4779 Acetyl-ACTH (2-24) (human, bovine, rat) Modulator / 否
HY-P4782 Acetyl-ACTH (3-24) (human, bovine, rat) Modulator / 否
HY-P4784 Acetyl-ACTH (4-24) (human, bovine, rat) Modulator / 否
HY-P4786 Acetyl-ACTH (7-24) (human, bovine, rat) / 否
HY-P4985 γ3-MSH / 否
HY-RS10865 POMC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17248 Pomc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23702 Pomc Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pomc NCBI NCBI:5443
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