2. Gene
  3. UCP1 - Ucp1 uncoupling protein 1 Gene

UCP1 - Ucp1 uncoupling protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ucp; Ucpa; Uncp

基因 ID: 24860 | 基因类型: protein coding

关于 UCP1

功能概要

Enables GDP binding activity; GTP binding activity; and Oxidative Phosphorylation uncoupler activity. Involved in several processes, including cellular response to hormone stimulus; cellular response to lipid; and proton transmembrane transport. Located in mitochondrion. Biomarker of prediabetes syndrome. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human UCP1 (uncoupling protein 1). [provided by Alliance of Genome Resources, Apr 2022]

UCP1 基因产物(1)

mRNA Protein Name
NM_012682.2 NP_036814.1 mitochondrial brown fat uncoupling protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GDP binding IDA
IDA: 通过直接分析推断
22952235 RGD
enables GTP binding IDA
IDA: 通过直接分析推断
12479871 RGD
enables oxidative phosphorylation uncoupler activity IDA
IDA: 通过直接分析推断
16451125 RGD
enables transmembrane transporter activity IMP
IMP: 通过突变表型推断
12479871 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to dehydroepiandrosterone IEP
IEP: 通过表达模式推断
12659879 RGD
involved in cellular response to fatty acid IDA
IDA: 通过直接分析推断
22952235 RGD
involved in cellular response to hormone stimulus IEP
IEP: 通过表达模式推断
18079609 RGD
involved in mitochondrial transmembrane transport IDA
IDA: 通过直接分析推断
22952235 RGD
involved in mitochondrial transport IDA
IDA: 通过直接分析推断
16814247 RGD
involved in proton transmembrane transport IDA
IDA: 通过直接分析推断
16814247 RGD
involved in proton transmembrane transport IMP
IMP: 通过突变表型推断
12479871 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
22952235 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitochondrial brown fat uncoupling protein 1

UCP 1

mitochondrial brown fat uncoupling protein 1-like

solute carrier family 25 member 7

thermogenin

uncoupling protein 1 (mitochondrial, proton carrier)

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107574 TC-E 5003 98.03% 否
HY-N0704 Agrimol B 99.75% 否
HY-110148 WWL113 Inhibitor 99.72% 否
HY-135115 Oleuropein Aglycone Inhibitor 98.46% 否
HY-153813 Z16078526 Modulator 98.13% 否
HY-133095 BML-260 Activator 99.65% 否
HY-129692 Withanone Inhibitor 93.28% 否
HY-148973 ZW290 Inhibitor 99.60% 否
HY-RS16955 Ucp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-176148 ZGL-18 / 否
HY-RS15410 UCP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-153812 AST 7062601 / 否
HY-RS23398 Ucp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens UCP1 NCBI NCBI:7350
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