2. Gene
  3. Hk1 - hexokinase 1 Gene

Hk1 - hexokinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: HKI; HEXOKIN

基因 ID: 25058 | 基因类型: protein coding

关于 Hk1

功能概要

Enables several functions, including ATP binding activity; glucose binding activity; and Hexokinase activity. Involved in several processes, including phosphorylation; response to ischemia; and response to ketamine. Located in caveola; cytosol; and mitochondrion. Part of protein-containing complex. Used to study obesity and urinary bladder Cancer. Biomarker of colorectal Cancer and pulmonary hypertension. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4G; anemia (multiple); hematologic Cancer (multiple); obesity; and retinitis pigmentosa. Orthologous to human HK1 (Hexokinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hk1 基因产物(2)

mRNA Protein Name
NM_001393711.1 NP_001380640.1 hexokinase-1 isoform 1
NM_012734.2 NP_036866.2 hexokinase-1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
15562563 RGD
enables D-glucose binding IDA
IDA: 通过直接分析推断
9665168 RGD
enables fructokinase activity IDA
IDA: 通过直接分析推断
5871820 RGD
enables glucokinase activity IDA
IDA: 通过直接分析推断
5871820 RGD
enables hexokinase activity IDA
IDA: 通过直接分析推断
2457393 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
9665168 RGD
enables mannokinase activity IDA
IDA: 通过直接分析推断
13211595 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16419038 RGD
enables protein kinase activity IDA
IDA: 通过直接分析推断
7531990 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
14561215 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in carbohydrate phosphorylation IDA
IDA: 通过直接分析推断
14561215 RGD
involved in fructose 6-phosphate metabolic process IDA
IDA: 通过直接分析推断
5871820 RGD
involved in glucose 6-phosphate metabolic process IDA
IDA: 通过直接分析推断
5871820 RGD
involved in glycolytic process IDA
IDA: 通过直接分析推断
4353083 RGD
involved in mannose metabolic process IDA
IDA: 通过直接分析推断
13211595 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
15574336 RGD
involved in peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
7531990 RGD
involved in peptidyl-threonine phosphorylation IDA
IDA: 通过直接分析推断
7531990 RGD
involved in peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
7531990 RGD
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
2059200 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
2059200 RGD
involved in regulation of anion channel activity IDA
IDA: 通过直接分析推断
14561215 RGD
involved in response to brassinosteroid IEP
IEP: 通过表达模式推断
20570616 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
29676955 RGD
involved in response to ischemia IDA
IDA: 通过直接分析推断
21410437 RGD
involved in response to ketamine IEP
IEP: 通过表达模式推断
22605548 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in caveola IDA
IDA: 通过直接分析推断
16419038 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
2457393 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
9459579 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hexokinase-1

brain form hexokinase

hexokinase type I

hexokinase-A

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N6954 Garcinone C 99.66% 否
HY-RS06192 HK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS06287 HOOK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07100 KCNA4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07373 KLK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14138 TAC4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17121 Hk1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23566 Hk1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hk1 NCBI NCBI:3098
Macaca fascicularis Hk1 NCBI NCBI:102145864
Mus musculus Hk1 NCBI NCBI:15275
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