2. Gene
  3. Pld1 - phospholipase D1 Gene

Pld1 - phospholipase D1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Plda; Pldb; Pld1a; Pld1b

基因 ID: 25096 | 基因类型: protein coding

关于 Pld1

功能概要

Enables Phospholipase D activity. Involved in phospholipid catabolic process; positive regulation of cell migration; and response to peptide hormone. Acts upstream of or within phosphatidic acid biosynthetic process. Located in Golgi cisterna; lamellipodium; and vesicle. Is active in synapse. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in developmental cardiac valvular defect. Orthologous to human PLD1 (Phospholipase D1). [provided by Alliance of Genome Resources, Apr 2022]

Pld1 基因产物(2)

mRNA Protein Name
NM_001399082.1 NP_001386011.1 phospholipase D1 isoform 1
NM_030992.3 NP_112254.2 phospholipase D1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phospholipase D activity IDA
IDA: 通过直接分析推断
12431982 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12431982 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within phosphatidic acid biosynthetic process IMP
IMP: 通过突变表型推断
18519738 RGD
acts upstream of or within phospholipid biosynthetic process IMP
IMP: 通过突变表型推断
18519738 RGD
involved in phospholipid catabolic process IMP
IMP: 通过突变表型推断
16459925 RGD
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
18344600 RGD
involved in response to peptide hormone IMP
IMP: 通过突变表型推断
16459925 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi cisterna IDA
IDA: 通过直接分析推断
12429836 RGD
located in lamellipodium IDA
IDA: 通过直接分析推断
18344600 RGD
is active in synapse IDA
IDA: 通过直接分析推断
11752468 RGD
located in vesicle IDA
IDA: 通过直接分析推断
18344600 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phospholipase D1

PLD 1

Phoshpolipase D gene 1 probably with two splicing variants A and B

choline phosphatase 1

phosphatidylcholine-hydrolyzing phospholipase D1

phospholipase D gene 1, probably with two splicing variants A and B

phospholipase D1, phosphatidylcholine-

相关产品

Pre-clinical Phase
生物活性分子 (15)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12807 FIPI Inhibitor 98.00% 否
HY-108612 VU0155069 Inhibitor 98.55% 否
HY-101293 VU0359595 Inhibitor 98.06% 否
HY-119093 Halopemide 99.65% 否
HY-155342 A3373 Inhibitor 99.06% 否
HY-108616 VU 0364739 hydrochloride Inhibitor / 否
HY-RS11140 PRKCSH Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-12807A FIPI hydrochloride Inhibitor / 否
HY-108612A VU0155069 hydrochloride Inhibitor / 否
HY-124305 ML395 / 否
HY-155343 A4333 Inhibitor / 否
HY-P10447 Plipastatin A1 Inhibitor / 否
HY-RS10670 PLD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19629 Pld1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26124 Pld1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pld1 NCBI NCBI:5337
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