2. Gene
  3. Cyp7a1 - cytochrome P450 family 7 subfamily A member 1 Gene

Cyp7a1 - cytochrome P450 family 7 subfamily A member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CHAP; CYP7; CYP7S1

基因 ID: 25428 | 基因类型: protein coding

关于 Cyp7a1

功能概要

Enables Cholesterol 7-alpha-monooxygenase activity. Involved in several processes, including bile acid biosynthetic process; cellular response to cholesterol; and regulation of lipid biosynthetic process. Located in intracellular membrane-bounded organelle. Biomarker of alcoholic hepatitis; cholestasis; extrahepatic cholestasis; and non-alcoholic steatohepatitis. Orthologous to human CYP7A1 (Cytochrome P450 family 7 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp7a1 基因产物(1)

mRNA Protein Name
NM_012942.2 NP_037074.1 cytochrome P450 7A1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cholesterol 7-alpha-monooxygenase activity IDA
IDA: 通过直接分析推断
1694852 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in bile acid and bile salt transport IEP
IEP: 通过表达模式推断
27939985 RGD
involved in bile acid biosynthetic process IDA
IDA: 通过直接分析推断
1694852 RGD
involved in cellular response to cholesterol IDA
IDA: 通过直接分析推断
1694852 RGD
involved in cholesterol catabolic process IDA
IDA: 通过直接分析推断
1694852 RGD
involved in cholesterol homeostasis IDA
IDA: 通过直接分析推断
1694852 RGD
involved in negative regulation of collagen biosynthetic process IMP
IMP: 通过突变表型推断
15521018 RGD
involved in negative regulation of fatty acid biosynthetic process IDA
IDA: 通过直接分析推断
23536474 RGD
involved in positive regulation of cholesterol biosynthetic process IDA
IDA: 通过直接分析推断
23536474 RGD
involved in regulation of bile acid biosynthetic process IDA
IDA: 通过直接分析推断
1694852 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
27939985 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
27939985 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in intracellular membrane-bounded organelle IDA
IDA: 通过直接分析推断
1694852 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytochrome P450 7A1

24-hydroxycholesterol 7-alpha-hydroxylase

CYPVII

cholesterol 7-alpha-hydroxylase

cholesterol 7-alpha-monooxygenase

cytochrome P450 (cholesterol hydroxylase 7 alpha)

cytochrome P450, 7a1

cytochrome P450, family 7, subfamily a, polypeptide 1

相关产品

Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-113259 7α-Hydroxy-4-cholesten-3-one 99.60% 否
HY-W008226 Phloracetophenone 99.96% 否
HY-117147A GSK2945 hydrochloride Activator 99.69% 否
HY-163436 F44-A13 96.73% 否
HY-117147 GSK2945 Activator / 否
HY-175266 MI1013 / 否
HY-RS03487 CYP7A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-168331 FXR agonist 10 Agonist / 否
HY-19264 264W94 / 否
HY-RS03488 CYP7B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174703 Human FGF19 mRNA / 否
HY-N13218 Pueraria Extract / 否
HY-RS17211 Cyp7a1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18706 Cyp7b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23663 Cyp7a1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25193 Cyp7b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp7a1 NCBI NCBI:1581
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