2. Gene
  3. Smad1 - SMAD family member 1 Gene

Smad1 - SMAD family member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Madh1

基因 ID: 25671 | 基因类型: protein coding

关于 Smad1

功能概要

Predicted to enable several functions, including SMAD binding activity; enzyme binding activity; and nucleic acid binding activity. Involved in several processes, including BMP signaling pathway; negative regulation of muscle cell apoptotic process; and positive regulation of dendrite morphogenesis. Located in cytoplasm and nucleus. Used to study pulmonary hypertension. Biomarker of glomerulonephritis; male infertility; nephrotic syndrome; and pulmonary hypertension. Orthologous to human SMAD1 (Smad Family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Smad1 基因产物(2)

mRNA Protein Name
NM_013130.3 NP_037262.3 mothers against decapentaplegic homolog 1
NM_013130.3 NP_037262.3 mothers against decapentaplegic homolog 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12552124 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in BMP signaling pathway IMP
IMP: 通过突变表型推断
16020542 RGD
involved in MAPK cascade IMP
IMP: 通过突变表型推断
16427075 RGD
involved in cardiac muscle hypertrophy in response to stress IMP
IMP: 通过突变表型推断
26873969 RGD
involved in kidney development IEP
IEP: 通过表达模式推断
11850197 RGD
involved in negative regulation of muscle cell apoptotic process IEP
IEP: 通过表达模式推断
11408477 RGD
involved in positive regulation of cell differentiation IDA
IDA: 通过直接分析推断
17525996 RGD
involved in positive regulation of dendrite morphogenesis IEP
IEP: 通过表达模式推断
15056710 RGD
involved in response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
18079356 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mothers against decapentaplegic homolog 1

MAD (mothers against decapentaplegic, Drosophila) homolog 1

MAD homolog 1

MAD homolog1 (mothers against decapentaplegic, Drosophila)

SMAD 1

SMAD, mothers against DPP homolog 1

mothers against DPP homolog 1

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-145608 Zilurgisertib Inhibitor 99.77% Phase 2
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99359 Elezanumab Inhibitor 99.91% Phase 2
HY-P99353 Ascrinvacumab Inhibitor 97.45% Phase 2
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-124697 BMP signaling agonist sb4 Agonist 99.98% 否
HY-12274 ML347 Inhibitor 99.94% 否
HY-108527 CD1530 98.01% 否
HY-164145 CDD-1653 99.38% 否
HY-123900 AZ12799734 Inhibitor 98.07% 否
HY-N0946 (-)-Pinoresinol 4-O-glucoside Inhibitor ≥98.0% 否
HY-173149 CDD-2789 Inhibitor / 否
HY-174416 Smurf1-IN-5 Inhibitor / 否
HY-RS05279 GARS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13392 SMAD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18190 Smad1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24664 Smad1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smad1 NCBI NCBI:4086
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