2. Gene
  3. Tfpi - tissue factor pathway inhibitor Gene

Tfpi - tissue factor pathway inhibitor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29436 | 基因类型: protein coding

关于 Tfpi

功能概要

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in cellular response to interleukin-1; cellular response to lipopolysaccharide; and response to estradiol. Located in extracellular space. Biomarker of atrial fibrillation; disseminated intravascular coagulation; myocardial infarction; and osteonecrosis. Human ortholog(s) of this gene implicated in several diseases, including Factor VIII deficiency; osteonecrosis; thrombophilia (multiple); toxic shock syndrome; and transient cerebral ischemia. Orthologous to human TFPI (tissue factor pathway inhibitor). [provided by Alliance of Genome Resources, Apr 2022]

Tfpi 基因产物(2)

mRNA Protein Name
NM_001177321.1 NP_001170792.1 tissue factor pathway inhibitor isoform 2 precursor
NM_017200.1 NP_058896.1 tissue factor pathway inhibitor isoform 1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
11816723 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
11816723 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
15857755 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
9426395 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12083485 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tissue factor pathway inhibitor

EPI

LACI

extrinsic pathway inhibitor

lipoprotein-associated coagulation inhibitor

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P99283 Concizumab 95.00% 否
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-153480A ARC19499 sodium Inhibitor 93.65% Phase 1
HY-153480 ARC19499 Inhibitor 93.65% Phase 1
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99725 Marstacimab 96.27% Phase 3
HY-P99465 Befovacimab Inhibitor 97.31% Phase 2
Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14427 TFPI Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14428 TFPI2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17298 Tfpi Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18411 Tfpi2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23753 Tfpi Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24892 Tfpi2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991379 MG1113A Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tfpi NCBI NCBI:7035
Mus musculus Tfpi NCBI NCBI:21788
Leporidae Tfpi NCBI
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