1. Gene
  2. Bmal1 - basic helix-loop-helix ARNT like 1 Gene

Bmal1 - basic helix-loop-helix ARNT like 1 Gene

种属: Rattus norvegicus

同用名: Arntl

基因 ID: 29657 | 基因类型: protein coding

关于 Bmal1

功能概要

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with Clock. This heterodimer binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. [provided by RefSeq, Jan 2014]

Bmal1 基因产物(1)

mRNA Protein Name
NM_024362.2 NP_077338.2 aryl hydrocarbon receptor nuclear translocator-like protein 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian rhythm IEP
IEP: 通过表达模式推断
9735336 RGD
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
22356123 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
22356123 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

aryl hydrocarbon receptor nuclear translocator-like protein 1

brain and muscle ARNT-like 1

tic

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bmal1 NCBI NCBI:406
Mus musculus Bmal1 NCBI