1. Gene
  2. Kat5 - K(lysine) acetyltransferase 5 Gene

Kat5 - K(lysine) acetyltransferase 5 Gene

种属: Mus musculus

同用名: PLIP; CPLA2; Tip55; Tip60; Htatip; Htatip1

基因 ID: 81601 | 基因类型: protein coding

关于 Kat5

功能概要

Enables peptide-lysine-N-acetyltransferase activity and transcription coactivator activity. Involved in peptidyl-lysine acetylation and positive regulation of Autophagy. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; eye; genitourinary system; hemolymphoid system gland; and limb. Orthologous to human KAT5 (lysine acetyltransferase 5). [provided by Alliance of Genome Resources, Apr 2022]

Kat5 基因产物(7)

mRNA Protein Name
NM_001199247.1 NP_001186176.1 histone acetyltransferase KAT5 isoform 2
NM_001199248.1 NP_001186177.1 histone acetyltransferase KAT5 isoform 3
NM_001199249.1 NP_001186178.1 histone acetyltransferase KAT5 isoform 4
NM_001362370.1 NP_001349299.1 histone acetyltransferase KAT5 isoform 5
NM_001362371.1 NP_001349300.1 histone acetyltransferase KAT5 isoform 5
NM_001362372.1 NP_001349301.1 histone acetyltransferase KAT5 isoform 6
NM_178637.2 NP_848752.1 histone acetyltransferase KAT5 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
30297459 MGI
enables histone acetyltransferase activity IMP
IMP: 通过突变表型推断
32542325 MGI
enables peptide-lysine-N-acetyltransferase activity IDA
IDA: 通过直接分析推断
22539723 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12464179 MGI
enables transcription coactivator activity IDA
IDA: 通过直接分析推断
12464179 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IDA
IDA: 通过直接分析推断
30297459 MGI
involved in apoptotic process IDA
IDA: 通过直接分析推断
30655546 MGI
involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
30655546 MGI
involved in double-strand break repair via homologous recombination IMP
IMP: 通过突变表型推断
30297459 MGI
involved in neural tube development IDA
IDA: 通过直接分析推断
30655546 MGI
involved in neurogenesis IDA
IDA: 通过直接分析推断
30655546 MGI
involved in peptidyl-lysine acetylation IDA
IDA: 通过直接分析推断
22539723 MGI
involved in positive regulation of autophagy IDA
IDA: 通过直接分析推断
22539723 MGI
involved in positive regulation of circadian rhythm IDA
IDA: 通过直接分析推断
31294688 MGI
involved in positive regulation of regulatory T cell differentiation IMP
IMP: 通过突变表型推断
24835996 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
15944124 MGI
involved in protein acetylation IMP
IMP: 通过突变表型推断
30655546 MGI
involved in regulation of hematopoietic stem cell differentiation IMP
IMP: 通过突变表型推断
32542325 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12464179 MGI
involved in sperm DNA condensation IMP
IMP: 通过突变表型推断
28694333 MGI
involved in spermatid development IMP
IMP: 通过突变表型推断
28694333 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of NuA4 histone acetyltransferase complex IDA
IDA: 通过直接分析推断
32542325 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
12464179 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

histone acetyltransferase KAT5

60 kDa Tat-interactive protein

HIV-1 tat interactive protein 1, 60 kDa homolog

HIV-1 tat interactive protein 1, homolog

Tat-interactive protein-60

histone acetyltransferase HTATIP

lysine acetyltransferase 5

protein 2-hydroxyisobutyryltransferase KAT

Kat5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Kat5 Q8CHK4 Atxn1 Mus musculus P54254 17110330
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kat5 NCBI NCBI:10524