2. Gene
  3. Pik3ap1 - phosphoinositide-3-kinase adaptor protein 1 Gene

Pik3ap1 - phosphoinositide-3-kinase adaptor protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: BCAP; 1810044J04Rik

基因 ID: 83490 | 基因类型: protein coding

关于 Pik3ap1

功能概要

Enables identical protein binding activity and phosphatidylinositol 3-kinase regulatory subunit binding activity. Involved in regulation of inflammatory response; regulation of signal transduction; and Toll-like Receptor signaling pathway. Located in cytosol and plasma membrane. Orthologous to human PIK3AP1 (phosphoinositide-3-kinase adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pik3ap1 基因产物(1)

mRNA Protein Name
NM_031376.4 NP_113553.1 phosphoinositide 3-kinase adapter protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
enables phosphatidylinositol 3-kinase regulatory subunit binding IDA
IDA: 通过直接分析推断
20728433 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11163197 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of toll-like receptor signaling pathway IMP
IMP: 通过突变表型推断
20728433 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
22187458 MGI
involved in positive regulation of toll-like receptor signaling pathway IMP
IMP: 通过突变表型推断
20728433 MGI
NOT involved in regulation of MAPK cascade IMP
IMP: 通过突变表型推断
22187458 MGI
NOT involved in regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
22187458 MGI
involved in regulation of inflammatory response IMP
IMP: 通过突变表型推断
22187460 MGI
involved in toll-like receptor 2 signaling pathway IMP
IMP: 通过突变表型推断
22187460 MGI
involved in toll-like receptor 4 signaling pathway IMP
IMP: 通过突变表型推断
22187458 MGI
involved in toll-like receptor 7 signaling pathway IMP
IMP: 通过突变表型推断
22187458 MGI
involved in toll-like receptor 9 signaling pathway IMP
IMP: 通过突变表型推断
22187458 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11163197 MGI
located in cytosol IDA
IDA: 通过直接分析推断
22187458 MGI
located in membrane IDA
IDA: 通过直接分析推断
22187458 MGI
NOT located in nucleus IDA
IDA: 通过直接分析推断
11163197 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11163197 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phosphoinositide 3-kinase adapter protein 1

B cell phosphoinositide 3-kinase adaptor

B-cell adapter for phosphoinositide 3-kinase

B-cell phosphoinositide 3-kinase adapter protein 1

Pik3ap1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Pik3ap1 Q9EQ32 Myd88 Mus musculus P22366
Anti Bait CoIP
22187460
种属内
Pik3ap1 Q9EQ32 Pik3ap1 Mus musculus Q9EQ32
Y2H
15102471
种属内
Pik3ap1 Q9EQ32 Tp53bp2 Mus musculus Q8CG79
Y2H
15102471
种属内
Pik3ap1 Q9EQ32 Tirap Mus musculus Q99JY1
Anti Bait CoIP
22187460
种属内
Pik3ap1 Q9EQ32 Nck1 Mus musculus Q99M51
Y2H
15102471
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10510 PIK3AP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22016 Pik3ap1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28534 Pik3ap1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pik3ap1 NCBI NCBI:118788
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